BACKGROUND While oocyte IVM is practiced sporadically it has not achieved widespread
clinical practice globally. However, recently there have been some seminal advances in our …

Modulation of phosphoinositide 3-kinase/protein kinase B/phosphatase and tensin
homologue (PI3K/AKT/PTEN) pathway in mammals yields mixed results. A deep …

Oocytes are maintained in a state of meiotic arrest following the first meiotic division until
ovulation is triggered. Within the antral follicle, meiotic arrest is actively suppressed in a …

Abstract Simulated Physiological Oocyte Maturation (SPOM) mimics in vitro the
physiological events of oocyte maturation. The system uses cAMP modulators in two steps …

Thousands of circular RNAs (circRNAs) have been recently discovered in cumulus cells and
oocytes from several species. However, the expression and function of circRNA during …

Rationale: It has been emergingly recognized that apoptosis generates plenty of
heterogeneous apoptotic vesicles (apoVs), which play a pivotal role in the maintenance of …

In vitro embryo production (IVEP) is an extremely important tool for genetic improvement in
livestock and it is the biotechnology that has grown the most recently. However, multiple …

The yak (Bos grunniens) is a unique breed living on the Qinghai–Tibet Plateau and its
surrounding areas, providing locals with a variety of vital means of living and production …

Simple Summary NOX4, PDE11A and GHR have previously been screened as candidate
genes for litter size in sheep. Therefore, it is necessary to validate these genes in the sheep …

This review presents the latest advances in and main obstacles to the application of in vitro
embryo production (IVEP) systems in small ruminants. This biotechnology is an extremely …