Plasma membrane channels formed by connexins: their regulation and functions

JC Sáez, VM Berthoud, MC Branes… - Physiological …, 2003 - journals.physiology.org
Sáez, Juan C., Viviana M. Berthoud, María C. Brañes, Agustín D. Martínez, and Eric C.
Beyer. Plasma Membrane Channels Formed by Connexins: Their Regulation and Functions …

Connections with connexins: the molecular basis of direct intercellular signaling

R Bruzzone, TW White, DL Paul - European journal of …, 1996 - Wiley Online Library
Adjacent cells share ions, second messengers and small metabotes through intercellular
channels which are present in gap junctions. This type of intercellular communication …

Physiological role of gap-junctional hemichannels: extracellular calcium-dependent isosmotic volume regulation

AP Quist, SK Rhee, H Lin, R Lal - The Journal of cell biology, 2000 - rupress.org
Hemichannels in the overlapping regions of apposing cells plasma membranes join to form
gap junctions and provide an intercellular communication pathway. Hemichannels are also …

[HTML][HTML] Paracrine signaling through plasma membrane hemichannels

N Wang, M De Bock, E Decrock, M Bol… - … et Biophysica Acta (BBA …, 2013 - Elsevier
Plasma membrane hemichannels composed of connexin (Cx) proteins are essential
components of gap junction channels but accumulating evidence suggests functions of …

[HTML][HTML] Structural organization of gap junction channels

GE Sosinsky, BJ Nicholson - Biochimica et Biophysica Acta (BBA) …, 2005 - Elsevier
Gap junctions were initially described morphologically, and identified as semi-crystalline
arrays of channels linking two cells. This suggested that they may represent an amenable …

Clustering of connexin 43–enhanced green fluorescent protein gap junction channels and functional coupling in living cells

FF Bukauskas, K Jordan… - Proceedings of the …, 2000 - National Acad Sciences
Communication-incompetent cell lines were transfected with connexin (Cx) 43 fused with
enhanced green fluorescent protein (EGFP) to examine the relation between Cx distribution …

[HTML][HTML] Conformational changes in surface structures of isolated connexin 26 gap junctions

DJ Müller, GM Hand, A Engel, GE Sosinsky - The EMBO journal, 2002 - embopress.org
Gap junction channels mediate communication between adjacent cells. Using atomic force
microscopy (AFM), we have imaged conformational changes of the cytoplasmic and …

Calcium-dependent open/closed conformations and interfacial energy maps of reconstituted hemichannels

J Thimm, A Mechler, H Lin, S Rhee, R Lal - Journal of Biological Chemistry, 2005 - ASBMB
Using an atomic force microscope, we have studied three-dimensional molecular
topography and calcium-sensitive conformational changes of individual hemichannels. Full …

Biological applications of the AFM: from single molecules to organs

S Kasas, NH Thomson, BL Smith… - … journal of imaging …, 1997 - Wiley Online Library
The application domains of the atomic force microscope have increased dramatically in
recent years. We present a short review of the contributions of this microscope to biology …

The role of connexin hemichannels in inflammatory diseases

B Peng, C Xu, S Wang, Y Zhang, W Li - Biology, 2022 - mdpi.com
Simple Summary Connexin hemichannels are formed by connexin protein family members,
and connect cytosol and extracellular milium. The function of connexin hemichannels cannot …