Oestrogens and their receptors contribute broadly to physiology and diseases. In
premenopausal women, endogenous oestrogens protect against cardiovascular, metabolic …

The actions of estrogens and related estrogenic molecules are complex and multifaceted in
both sexes. A wide array of natural, synthetic, and therapeutic molecules target pathways …

Nuclear-and membrane-initiated estrogen signaling cooperate to orchestrate the pleiotropic
effects of estrogens. Classical estrogen receptors (ERs) act transcriptionally and govern the …

One of the major causes of morbidity and mortality worldwide is cardiac hypertrophy (CH),
which leads to heart failure. Sex differences in CH can be caused by sex hormones or their …

Estrogens can alter the biology of various tissues and organs, including the brain, and thus
play an essential role in modulating homeostasis. Despite its traditional role in reproduction …

Background Traumatic brain injury (TBI) is an important and growing cause of disability
worldwide, and its cognitive consequences may be particularly significant. This study …

Introduction The aim of this study was to determine the anti-inflammatory effect of female sex
hormones on the level of intracellular molecules of cytokine signaling pathway after diffuse …

Background Studies have confirmed the salutary effects of progesterone (P4) on traumatic
brain injury (TBI). This study investigated the beneficial effects of P4 via its receptors on TBI …

Daidzein Mitigates Oxidative Stress and Inflammation in the Injured Kidney of
Ovariectomized Rats: AT1 and Mas Receptor Function Page 1 KIDNEY DISEASES 32 …

Abstract Estrogens, particularly 17β-estradiol (estradiol, E 2), regulate memory formation. E2
acts through its intracellular receptors, estrogen receptors (ER) ERα and ERβ, as well as a …