Radiomic signatures derived from diffusion-weighted imaging for the assessment of breast cancer receptor status and molecular subtypes

D Leithner, B Bernard-Davila, DF Martinez… - Molecular imaging and …, 2020 - Springer
Purpose To compare annotation segmentation approaches and to assess the value of
radiomics analysis applied to diffusion-weighted imaging (DWI) for evaluation of breast …

A machine learning framework develops a DNA replication stress model for predicting clinical outcomes and therapeutic vulnerability in primary prostate cancer

RH Huang, YK Hong, H Du, WQ Ke, BB Lin… - Journal of Translational …, 2023 - Springer
Recent studies have identified DNA replication stress as an important feature of advanced
prostate cancer (PCa). The identification of biomarkers for DNA replication stress could …

The risk correlation between N7‐methylguanosine modification‐related lncRNAs and survival prognosis of oral squamous cell carcinoma based on comprehensive …

Y Xu, X Zou, J Mei - Applied Bionics and Biomechanics, 2022 - Wiley Online Library
Objective. N7‐methylguanosine modification‐related lncRNAs (m7G‐related lncRNAs) are
involved in progression of many diseases. This study was aimed at revealing the risk …

Identification of egfr as a novel key gene in clear cell renal cell carcinoma (ccrcc) through bioinformatics analysis and meta‐analysis

S Wang, Z Yu, K Chai - BioMed research international, 2019 - Wiley Online Library
Clear cell renal cell carcinoma (ccRCC) was the most aggressive histological type of renal
cell carcinoma (RCC) and accounted for 70–80% of cases of all RCC. The aim of this study …

Identification of expression profiles and prognostic value of RFCs in colorectal cancer

M Misbah, M Kumar, AK Najmi, M Akhtar - Scientific Reports, 2024 - nature.com
Colorectal cancer (CRC) ranks among the most prevalent cancers globally, with its
incidence closely tied to DNA damage. The Replication Factor C (RFC) complexes …

RFC2 promotes aerobic glycolysis and progression of colorectal cancer

F Lou, M Zhang - BMC gastroenterology, 2023 - Springer
Background Replication factor C subunit 2 (RFC2) participates in the growth and metastasis
of various malignancies. Our study investigated the roles of RFC2 in colorectal cancer …

Exploring the molecular mechanism of the drug-treated breast cancer based on gene expression microarray

AM Alshabi, B Vastrad, IA Shaikh, C Vastrad - Biomolecules, 2019 - mdpi.com
Breast cancer (BRCA) remains the leading cause of cancer morbidity and mortality
worldwide. In the present study, we identified novel biomarkers expressed during estradiol …

AEG-1 Knockdown Sensitizes Glioma Cells to Radiation Through Impairing Homologous Recombination Via Targeting RFC5

X Zhao, Y Sun, X Sun, J Li, X Shi, Z Liang, Y Ma… - DNA and cell …, 2021 - liebertpub.com
Radiotherapy is the most important adjuvant treatment for glioma; however, radioresistance
is the major cause for inevitable recurrence and poor survival of glioma patients. Thus, this …

[HTML][HTML] The role of long non-coding RNA LINC01296 in oral squamous cell carcinoma: a study based on bioinformatics analysis and in vitro validation

K Yang, L Li, Y Chen, S Man, L Yang, Y Yang… - Journal of …, 2022 - ncbi.nlm.nih.gov
Background: Oral squamous cell carcinoma (OSCC) is a common malignancy in the oral
cavity that represents a significant global health problem. Multivariate analysis has shown …

Identifying the hub genes in non-small cell lung cancer by integrated bioinformatics methods and analyzing the prognostic values

T Wang, X Chen, F Jing, Z Li, H Tan, Y Luo… - Pathology-Research and …, 2021 - Elsevier
Background Lung cancer, a malignant tumor, has the highest mortality and second most
common morbidity worldwide. Non-small cell lung cancer (NSCLC) is the most common …