Simple Summary Lipopolysaccharide (LPS) derived from intestinal bacteria is linked to long-
lasting inflammation that contributes to the development of intestinal cancer. While much …

Crystallins, the major constituent proteins of mammalian lenses, are significant not only for
the maintenance of eye lens stability, transparency, and refraction, but also fulfill various …

High-altitude pulmonary hypertension (HAPH) is a complication arising from an inability to
acclimatize to high altitude and is associated with high morbidity and mortality. We aimed to …

Drug metabolizing enzymes catalyze the biotransformation of many of drugs and chemicals.
The drug metabolizing enzymes are distributed among several evolutionary families and …

Breast cancer is the most frequently diagnosed malignant tumor in women and a major
public health concern. NRF2 axis is a cellular protector signaling pathway protecting both …

Background Ovarian cancer is the deadliest gynaecological tumour. In agreement with the
National Comprehensive Cancer Network (NCCN) Guidelines for Ovarian Cancer and with …

Soluble quinone oxidoreductases catalyze transfer of electrons from NADPH to quinones.
Transfer of electrons is essential for detoxification of synthetic compounds. Here, we present …

It was hypothesized that the longissimus thoracis (LT) muscle proteome, phosphoproteome,
and metabolome could explain postmortem metabolism and tenderness differences in …

Crystallin zeta (CRYZ) is a phylogenetically restricted water-soluble protein and provides
cytoprotection against oxidative stress via multiple mechanisms. Increasing evidence …

Background Clear cell renal cell carcinoma (ccRCC), the most prevalent kidney cancer
subtype, has a high mortality rate. Crystallin lambda 1 (CRYL1) encodes an enzyme that …