A new class of biological ion-driven rotary molecular motors with 5: 2 symmetry

M Rieu, R Krutyholowa, NMI Taylor… - Frontiers in …, 2022 - frontiersin.org
Several new structures of three types of protein complexes, obtained by cryo-electron
microscopy (cryo-EM) and published between 2019 and 2021, identify a new family of …

A journey with type IX secretion system effectors: selection, transport, processing and activities

M Paillat, I Lunar Silva, E Cascales… - Microbiology, 2023 - microbiologyresearch.org
The type IX secretion system (T9SS) is a multiprotein machine distributed in Bacteroidota
and responsible for the secretion of various proteins across the outer membrane. Secreted …

Dynamic proton-dependent motors power type IX secretion and gliding motility in Flavobacterium

MS Vincent, C Comas Hervada, C Sebban-Kreuzer… - PLoS …, 2022 - journals.plos.org
Motile bacteria usually rely on external apparatus like flagella for swimming or pili for
twitching. By contrast, gliding bacteria do not rely on obvious surface appendages to move …

Filamentous structures in the cell envelope are associated with bacteroidetes gliding machinery

S Shibata, YO Tahara, E Katayama… - Communications …, 2023 - nature.com
Many bacteria belonging to the phylum Bacteroidetes move on solid surfaces, called gliding
motility. In our previous study with the Bacteroidetes gliding bacterium Flavobacterium …

Structural insights into the mechanism of protein transport by the Type 9 Secretion System translocon

F Lauber, JC Deme, X Liu, A Kjær, HL Miller… - Nature …, 2024 - nature.com
Secretion systems are protein export machines that enable bacteria to exploit their
environment through the release of protein effectors. The Type 9 Secretion System (T9SS) is …

[HTML][HTML] Structural model of a Porphyromonas gingivalis type IX secretion system shuttle complex

B Dorgan, Y Liu, S Wang, J Aduse-Opoku… - Journal of Molecular …, 2022 - Elsevier
Porphyromonas gingivalis is a gram-negative oral anaerobic pathogen and is one of the key
causative agents of periodontitis. P. gingivalis utilises a range of virulence factors, including …

Structure–function analysis of PorXFj, the PorX homolog from Flavobacterium johnsioniae, suggests a role of the CheY-like domain in type IX secretion motor activity

M Zammit, J Bartoli, C Kellenberger, P Melani… - Scientific Reports, 2024 - nature.com
The type IX secretion system (T9SS) is a large multi-protein transenvelope complex
distributed into the Bacteroidetes phylum and responsible for the secretion of proteins …

[HTML][HTML] Discovery of a novel marine Bacteroidetes with a rich repertoire of carbohydrate-active enzymes

B Chen, G Liu, Q Chen, H Wang, L Liu… - Computational and …, 2024 - Elsevier
Members of the phylum Bacteroidetes play a key role in the marine carbon cycle through
their degradation of polysaccharides via carbohydrate-active enzymes (CAZymes) and …

Protein interactome mapping of Porphyromonas gingivalis provides insights into the formation of the PorQ‐Z complex of the type IX secretion system

DG Gorasia, PD Veith… - Molecular Oral …, 2023 - Wiley Online Library
Porphyromonas gingivalis is an anaerobic Gram‐negative human oral pathogen highly
associated with the more severe forms of periodontal disease. Porphyromonas gingivalis …

A pleiotropic role of sialidase in the pathogenicity of Porphyromonas gingivalis

C Pham, S Guo, X Han, L Coleman, CW Sze… - Infection and …, 2024 - Am Soc Microbiol
As one of the keystone pathogens of periodontitis, the oral bacterium Porphyromonas
gingivalis produces an array of virulence factors, including a recently identified sialidase …