Neuropathic pain

L Colloca, T Ludman, D Bouhassira, R Baron… - Nature reviews Disease …, 2017 - nature.com
Neuropathic pain is caused by a lesion or disease of the somatosensory system, including
peripheral fibres (Aβ, Aδ and C fibres) and central neurons, and affects 7–10% of the …

Etiology and pharmacology of neuropathic pain

SRA Alles, PA Smith - Pharmacological reviews, 2018 - ASPET
Injury to or disease of the nervous system can invoke chronic and sometimes intractable
neuropathic pain. Many parallel, interdependent, and time-dependent processes, including …

[HTML][HTML] Peripheral neuropathic pain: a mechanism-related organizing principle based on sensory profiles

R Baron, C Maier, N Attal, A Binder, D Bouhassira… - Pain, 2017 - journals.lww.com
Patients with neuropathic pain are heterogeneous in etiology, pathophysiology, and clinical
appearance. They exhibit a variety of painrelated sensory symptoms and signs (sensory …

Neuropathic pain: mechanism-based therapeutics

K Bannister, J Sachau, R Baron… - Annual review of …, 2020 - annualreviews.org
Neuropathic pain (NeP) can result from sources as varied as nerve compression,
channelopathies, autoimmune disease, and incision. By identifying the neurobiological …

Diagnosis and assessment of neuropathic pain through questionnaires

N Attal, D Bouhassira, R Baron - The Lancet Neurology, 2018 - thelancet.com
Neuropathic pain—pain caused by a lesion or disease of the somatosensory nervous
system—is underdiagnosed and difficult to treat. However, development of easy-to-use …

[HTML][HTML] Stratifying patients with peripheral neuropathic pain based on sensory profiles: algorithm and sample size recommendations

J Vollert, C Maier, N Attal, DLH Bennett, D Bouhassira… - Pain, 2017 - journals.lww.com
In a recent cluster analysis, it has been shown that patients with peripheral neuropathic pain
can be grouped into 3 sensory phenotypes based on quantitative sensory testing profiles …

Pharmacological treatments of neuropathic pain: The latest recommendations

N Attal - Revue neurologique, 2019 - Elsevier
We provide an up-to-date review of the pharmacological treatment of neuropathic pain with
emphasis on the latest evidence-based recommendations for its pharmacological treatment …

Carbonic anhydrase inhibition and the management of neuropathic pain

CT Supuran - Expert review of neurotherapeutics, 2016 - Taylor & Francis
Introduction: Neuropathic pain affects up to 8% of the population with few therapeutic
options for its management. No specific drugs are approved for its treatment. Areas covered …

Stratification of patients based on the Neuropathic Pain Symptom Inventory: development and validation of a new algorithm

D Bouhassira, S Branders, N Attal, AM Fernandes… - Pain, 2021 - journals.lww.com
The personalization of neuropathic pain treatment could be improved by identifying specific
sensory phenotypes (ie, specific combinations of symptoms and signs) predictive of the …

Calcium channel modulation as a target in chronic pain control

R Patel, C Montagut‐Bordas… - British Journal of …, 2018 - Wiley Online Library
Neuropathic pain remains poorly treated for large numbers of patients, and little progress
has been made in developing novel classes of analgesics. To redress this issue, ziconotide …