[HTML][HTML] Biomarkers in the diagnosis and prognosis of sarcoidosis: current use and future prospects

R Kraaijvanger, M Janssen Bonás… - Frontiers in …, 2020 - frontiersin.org
Sarcoidosis is a heterogeneous disease in terms of presentation, duration, and severity. Due
to this heterogeneity, it is difficult to align treatment decisions. Biomarkers have proved to be …

[HTML][HTML] Club cell secreted protein CC16: potential applications in prognosis and therapy for pulmonary diseases

S Almuntashiri, Y Zhu, Y Han, X Wang… - Journal of clinical …, 2020 - mdpi.com
Club cell secretory protein (CC16) is encoded by the SCGB1A1 gene. It is also known as
CC10, secretoglobin, or uteroglobin. CC16 is a 16 kDa homodimeric protein secreted …

Neurosarcoidosis: clinical manifestations, investigation and treatment

DP Kidd - Practical Neurology, 2020 - pn.bmj.com
Sarcoidosis affects the nervous system in 10% of cases. When it does so it can affect any
part of the nervous system and with all degrees of severity. It forms part of the differential …

[HTML][HTML] Sarcoidosis-related uveitis: a review

S Giorgiutti, R Jacquot, T El Jammal, A Bert… - Journal of clinical …, 2023 - mdpi.com
Sarcoidosis is an inflammatory disease that involves the eyes in 10–55% of cases,
sometimes without systemic involvement. All eye structures can be affected, but uveitis is the …

Krebs von den Lungen-6 as a biomarker for disease severity assessment in interstitial lung disease: a comprehensive review

M d'Alessandro, L Bergantini, P Cameli… - Biomarkers in …, 2020 - Taylor & Francis
Aim: Interstitial lung diseases (ILD) are a group of lung disorders characterized by interstitial
lung thickening. Krebs von den Lungen-6 (KL-6) is a molecule that is predominantly …

BAL biomarkers' panel for differential diagnosis of interstitial lung diseases

M d'Alessandro, A Carleo, P Cameli… - Clinical and …, 2020 - Springer
Bronchoalveolar lavage (BAL) is a useful procedure for differential diagnosis of interstitial
lung diseases (ILDs) and for identification of granulomatous lung diseases. We investigated …

Transcriptomics of bronchoalveolar lavage cells identifies new molecular endotypes of sarcoidosis

M Vukmirovic, X Yan, KF Gibson… - European …, 2021 - Eur Respiratory Soc
Background Sarcoidosis is a multisystem granulomatous disease of unknown origin with a
variable and often unpredictable course and pattern of organ involvement. In this study we …

New concepts in the pathogenesis of sarcoidosis

D Bennett, E Bargagli, RM Refini… - Expert Review of …, 2019 - Taylor & Francis
Introduction: The pathogenesis of sarcoidosis is not yet completely understood, although in
recent years our knowledge has made considerable progress. Areas covered: This review …

Personalized medicine in sarcoidosis: unravelling biomarkers for targeted care

J Francesqui, P Marrades… - Current opinion in …, 2023 - journals.lww.com
These findings have implications for clinical practice and research. The limitations of
established biomarkers underscore the need for improved diagnostic tools in sarcoidosis …

NK and NKT-like cells in granulomatous and fibrotic lung diseases

L Bergantini, P Cameli, M d'Alessandro… - Clinical and …, 2019 - Springer
Background The pathogenetic and regulatory roles of natural killer (NK) and natural killer T-
like cells in interstitial lung diseases (ILDs), fibrotic and granulomatous of unknown etiology …