Covariates in population pharmacokinetic studies of critically ill adults receiving β-lactam antimicrobials: a systematic review and narrative synthesis

J Hansel, F Mannan, R Robey… - JAC-Antimicrobial …, 2024 - academic.oup.com
Introduction Population pharmacokinetic studies of β-lactam antimicrobials in critically ill
patients derive models that inform their dosing. In non-linear mixed-effects modelling …

Relationship between Target Time above Minimum Inhibitory Concentration Achievement Rate of Meropenem Using Monte Carlo Simulation and In-Hospital Survival …

H Nakashima, M Miyazaki, T Kuwamura, K Oda… - Antibiotics, 2024 - mdpi.com
Pseudomonas aeruginosa bacteremia is associated with a high mortality rate, and
meropenem (MEPM) is commonly used to treat it. However, the relationship between the …

A UHPLC–MS/MS method for the simultaneous determination of vancomycin, norvancomycin, meropenem, and moxalactam in human plasma and its clinical …

J Huo, Y Guo, B Zhang, Z Zhao, G Shi… - Journal of Mass …, 2023 - Wiley Online Library
We developed an ultra‐high‐performance liquid chromatography–tandem mass
spectrometry (UHPLC–MS/MS) method to determine four antibacterial drugs in human …

Meropenem pharmacokinetics and target attainment in critically ill patients

Y Gan, X Meng, N Lei, H Yu, Q Zeng… - Infection and Drug …, 2023 - Taylor & Francis
Purpose This study aimed to investigate the pharmacokinetics and target attainment of
meropenem and compare the effect of meropenem dosing regimens in critically ill patients …

Population pharmacokinetics, dosing optimization and clinical outcomes of biapenem in patients with sepsis

D Chen, X Wu, H Zhang, H Yao, L Jin, X Luo… - Frontiers in …, 2024 - frontiersin.org
Introduction: Biapenem is a carbapenem antibiotic widely used in Asia, can be used for the
treatment of adults and children with infections due to susceptible bacteria. Although …

Usage of Meropenem Continuous Infusion for Treatment of Infectious Complications in Orthopedic Elderly Patients with Anemia: A Case Series

A Konkayev, A Kadralinova, B Azimova, D Tazhibayeva… - Medicina, 2024 - mdpi.com
Background and Objectives: The prolonged infusion of meropenem is recommended by
guidelines for the treatment of sepsis. However, studies provide controversial data on the …

Piperacillin‐tazobactam dosing in anuric acute kidney injury patients receiving continuous renal replacement therapy

D Rungkitwattanakul, T Charoensareerat… - Seminars in …, 2023 - Wiley Online Library
Introduction: To determine appropriate dosing of piperacillin‐tazobactam in critically ill
patients receiving continuous renal replacement therapy (CRRT). Methods: The databases …

Obesitatearen inpaktua ß-laktamiko antipseudomonikoen portaera farmakozinetiko/farmakodinamikoan paziente kritikoetan. Egokia al da egungo dosifikazioa?

U Etxeberria Iztueta - 2023 - addi.ehu.es
Antibiotikoekiko erresistentzia gora doan honetan, hilkortasun tasa altua duen paziente
kritikoen populazioa aztertu eta hauentzako dosifikazio erregimenik aproposena …

[PDF][PDF] Pharmaceutical Sciences Asia

P Sanguanwit, P Montakantikul, P Damrongkulchart… - pharmacy.mahidol.ac.th
In sepsis and septic shock, patients often face hemodynamic instability, resulting in fluid
leakage, heightened capillary permeability, increased distribution volume, and …

Dose optimization of meropenem for critically ill patients by pharmacokinetic/pharmacodynamic simulation

NT Cuc, NH Anh, NTN Tien, NDM Vuong… - Tạp chí Nghiên cứu …, 2023 - jprdi.vn
Meropenem is a broad-spectrum carbapenem antibiotic which is commonly prescribed for
treatment of severe infections caused by multidrug-resistant bacteria [1]. In critically ill …