Endothelium‐dependent hyperpolarizing factor (EDHF) is a powerful vasodilator influence in
small resistance arteries and thus an important modulator of blood pressure and flow. As the …

Endothelial cells synthesize and release vasoactive mediators in response to various
neurohumoural substances (eg bradykinin or acetylcholine) and physical stimuli (eg cyclic …

The term endothelium-derived hyperpolarising factor (EDHF) was introduced in 1987 to
describe the hypothetical factor responsible for myocyte hyperpolarisations not associated …

The endothelium plays an important role in maintaining vascular homeostasis by
synthesizing and releasing several endothelium-derived relaxing factors, such as …

Our view of the endothelium was transformed around 30 years ago, from one of an inert
barrier to that of a key endocrine organ central to cardiovascular function. This dramatic …

An endothelium‐derived hyperpolarizing factor (EDHF) that is distinct from nitric oxide (NO)
and prostanoids has been widely hypothesized to hyperpolarize and relax vascular smooth …

The control and maintenance of vascular tone is due to a balance between vasoconstrictor
and vasodilator pathways. Vasomotor responses to neural, metabolic and physical factors …

Le facteur hyperpolarisant provenant de l'endothélium, ou EDHF, est défini comme la
substance non-monoxyde d'azote (NO) et non-prostacycline (PGI2) qui véhicule …

The elusive nature of endothelium‐derived hyperpolarizing factor (EDHF) has hampered
detailed study of the ionic mechanisms that underlie the EDHF hyperpolarization and …

There is now strong evidence that an endothelial mechanism, other than nitric oxide or
prostacyclin, exists for dilating arteries and arterioles. This third pathway has been named …