Metabolic syndrome is a cluster of conditions associated with the risk of diabetes mellitus
type 2 and cardiovascular diseases (CVDs). Metabolic syndrome is closely related to …

Mitochondria are central hubs for energy production, metabolism and cellular signal
transduction in eukaryotic cells. Maintenance of mitochondrial homeostasis is important for …

Stem cells perform many different functions, each of which requires specific metabolic
adaptations. Over the past decades, studies of pluripotent and tissue stem cells have …

The tricarboxylic acid (TCA) cycle is a primordial metabolic pathway that is conserved from
bacteria to humans. Although this network is often viewed primarily as an energy producing …

The oxidative tricarboxylic acid (TCA) cycle is a central mitochondrial pathway integrating
catabolic conversions of NAD+ to NADH and anabolic production of aspartate, a key amino …

Steatotic liver diseases (SLDs) affect one-third of the population, but the pathogenesis
underlying these diseases is not well understood, limiting the available treatments. A …

Introduction: Systemic sclerosis (SSc) is a chronic autoimmune disease, marked by an
unpredictable course, high morbidity, and increased mortality risk that occurs especially in …

Although elevated cholesterol and other recognised cardiovascular risk factors are important
in the development of coronary artery disease (CAD) and heart attack, the susceptibility of …

In Alzheimer's disease (AD), dysfunctional mitochondrial metabolism is associated with
synaptic loss, the major pathological correlate of cognitive decline. Mechanistic insight for …

In the context of Nigeria's societal advancement regarding consumers' economic status,
access to food, nutritional well-being, and overall health, traditional fermented foods play a …