The risks, measurements of severity, and management of severe acute pancreatitis and its
complications have evolved rapidly over the past decade. Evidence suggests that initial goal …

Acute pancreatitis (AP) is an inflammatory disease that can progress to severe acute
pancreatitis (SAP), which increases the risk of death. AP is characterized by inappropriate …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Acute pancreatitis (AP), an acute inflammatory disorder of the exocrine pancreas, is one of
the most common gastrointestinal diseases encountered in emergency departments with no …

Pancreatitis is a common, sometimes fatal, disease of exocrine pancreas, initiated by
damaged acinar cells. Recent studies implicate disordered macroautophagy/autophagy in …

Recent studies have highlighted the importance of autophagy and particularly non-
canonical autophagy in the development and progression of acute pancreatitis (a frequent …

Regulated exocytosis is initiated by increased Ca2+ concentrations in close spatial proximity
to secretory granules, which is effectively prevented when the cell is at rest. Here we showed …

Acute pancreatitis (AP) is an inflammatory disease of the pancreas. The severity is classified
as mild (MAP), moderately severe (MSAP), or severe (SAP). In patients with SAP, organ …

Excessive alcohol intake is a major risk factor for pancreatitis, sensitizing the exocrine
pancreas to stressors by mechanisms that remain obscure. Impaired autophagy drives …

Acute pancreatitis is characterized by necrosis of its parenchymal cells and influx and
activation of inflammatory cells that further promote injury and necrosis. This review is …