Since their inception, rhodamine dyes have been extensively applied in biotechnology as
fluorescent markers or for the detection of biomolecules owing to their good optical physical …

The first matrix metalloproteinase (MMP) was discovered in 1962 from the tail of a tadpole by
its ability to degrade collagen. As their name suggests, matrix metalloproteinases are …

Platinum-based drugs cisplatin, carboplatin, and oxaliplatin are widely used for
chemotherapeutic eradication of cancer. However, the side effects of platinum drugs, such …

The discovery of a near-infrared (NIR, 650–900 nm) fluorescent chromophore hemicyanine
dye with high structural tailorability is of great significance in the field of detection …

Near-infrared (NIR) fluorophores have unique features that endow them with several
advantages over conventional shorter wavelength emitting dyes. As a result, they have been …

As the main biomarkers of most diseases, enzymes play fundamental but extremely critical
roles in biosystems. High-resolution studies of enzymes using activatable in situ …

Small-molecule based fluorescent probes are increasingly important for the detection and
imaging of biological signaling molecules due to their simplicity, high selectivity and …

Mitochondria are not only the main energy source of the cell but are also involved in the
regulation of important physiology and processes of diseases including cancers. Therefore …

Molecular activatable probes with near‐infrared (NIR) fluorescence play a critical role in in
vivo imaging of biomarkers for drug screening and disease diagnosis. With structural …

Hepatic ischemia–reperfusion injury (HIRI) is responsible for postoperative liver dysfunction
and liver failure. Precise and rapid navigation of HIRI lesions is critical for early warning and …