[HTML][HTML] Predictive biomarkers for checkpoint inhibitor immune-related adverse events

I Les, M Martinez, I Perez-Francisco, M Cabero… - Cancers, 2023 - mdpi.com
Simple Summary Immune-checkpoint inhibitors (ICIs) are increasingly used in the treatment
of cancer, but they cause immune-related adverse events (irAEs) in around 40% of patients …

Risk factors for immune checkpoint inhibitor-related pneumonitis in cancer patients: a systemic review and meta-analysis

P Zhou, X Zhao, G Wang - Respiration, 2022 - karger.com
Abstract Background: Immune checkpoint inhibitors (ICIs) can lead to one of the common
and quite serious immune-related adverse events (irAEs) in a real-world setting, namely …

Immune checkpoint inhibitor‐related adverse events in lung cancer: Real‐world incidence and management practices of 1905 patients in China

Y Shi, J Fang, C Zhou, A Liu, Y Wang, Q Meng… - Thoracic …, 2022 - Wiley Online Library
Abstract Background Immune checkpoint inhibitors (ICIs) are the standard treatment for
advanced lung cancer, but immune‐related adverse events (irAEs) remain poorly …

Association between pretreatment C-reactive protein level and survival in non-small cell lung cancer patients treated with immune checkpoint inhibitors: A meta …

H Wang, R Yang, K Zhou, S Wang, C Cheng… - International …, 2023 - Elsevier
Background Current evidence suggests that C-reactive protein (CRP) levels may affect
cancer prognosis. However, the effect of CRP has not been validated in immunotherapy …

A Risk-Scoring Model for Severe Checkpoint Inhibitor-Related Pneumonitis: A Case–Control Study

H Deng, J Deng, X Lin, W Guan, Z Lin, Y Qiu… - Clinical Drug …, 2023 - Springer
Abstract Background and Objective Checkpoint inhibitor-related pneumonitis (CIP) is one of
the most common serious and fatal adverse events associated with immune checkpoint …

[HTML][HTML] Associations between patient and disease characteristics and severe adverse events during immune checkpoint inhibitor treatment: an observational study

EA Basak, NS Vermeer, K de Joode… - European Journal of …, 2022 - Elsevier
Aim With increasing use of immune checkpoint inhibitors (ICIs) more patients will develop
severe and potentially life-threatening immune-related adverse events (irAEs). So far …

[HTML][HTML] Immune-related adverse events, biomarkers of systemic inflammation, and survival outcomes in patients receiving pembrolizumab for non-small-cell lung …

G Raynes, M Stares, S Low, D Haron, H Sarwar, D Abhi… - Cancers, 2023 - mdpi.com
Simple Summary Immune checkpoint inhibitors offer the chance for the durable disease
control of advanced/metastatic non-small-cell lung cancer (NSCLC). However, they come …

[HTML][HTML] Immune checkpoint inhibitor-induced myositis/myocarditis with myasthenia gravis-like misleading presentation: a case series in intensive care unit

F Deharo, J Carvelli, J Cautela, M Garcia… - Journal of Clinical …, 2022 - mdpi.com
Introduction: Immune checkpoint inhibitors (ICIs) are a major breakthrough in cancer
treatment. Their increasingly frequent use leads to an uprising incidence of immune-related …

Immune checkpoint inhibitors as first-line therapy for non-small cell lung cancer: A systematic evaluation and meta-analysis

Y Lu, X Zhang, J Ning, M Zhang - Human Vaccines & …, 2023 - Taylor & Francis
Recently, immune checkpoint inhibitors (ICIs) present promising application prospects in
treating non-small cell lung cancer (NSCLC). This study aimed to investigate optimal …

Predictive value of NLR and PLR for immune-related adverse events: a systematic review and meta-analysis

HR Lu, PF Zhu, YY Deng, ZL Chen, L Yang - Clinical and Translational …, 2024 - Springer
Background Currently, there is a lack of affordable and accessible indicators that can
accurately predict immune-related adverse events (irAEs) resulting from the use of immune …