Pig-to-nonhuman primate islet xenotransplantation: a review of current problems
PPM Rood, LH Buhler, R Bottino, M Trucco… - Cell …, 2006 - journals.sagepub.com
Islet allotransplantation has been shown to have potential as a treatment for type 1 diabetic
patients. Xenotransplantation, using the pig as a donor, offers the possibility of an unlimited …
patients. Xenotransplantation, using the pig as a donor, offers the possibility of an unlimited …
Isolation of adult porcine islets of Langerhans
C Toso, D Brandhorst, J Oberholzer… - Cell …, 2000 - journals.sagepub.com
While human islet allotransplantation is limited due to the shortage of donors, pig islet
xenotransplantation appears to be a possible alternative. Enzymatic digestion is the method …
xenotransplantation appears to be a possible alternative. Enzymatic digestion is the method …
Selective removal of contaminants from a surface using articles having magnets
DW Koenig, BM Nelson, BA Lange - US Patent 6,503,761, 2003 - Google Patents
A system and method for removing contaminants from a surface. The system is designed to
use particles having means thereon which are capable of selectively binding to a …
use particles having means thereon which are capable of selectively binding to a …
Selective removal of contaminants from a surface using colored particles and articles having magnets
DW Koenig - US Patent 6,841,393, 2005 - Google Patents
Surface. The System is designed to use very Small particles having means thereon which
are capable of Selectively binding to a contaminant or contaminants of interest. The particles …
are capable of Selectively binding to a contaminant or contaminants of interest. The particles …
Stable transplantation results of magnetically retracted islets: a novel method
GGM Pinkse, E Steenvoorde, S Hogendoorn… - Diabetologia, 2004 - Springer
Aims/hypothesis Large quantities of pure viable donor islets are necessary for clinical
transplantation. At present, low yields and low viability of pancreatic islets after …
transplantation. At present, low yields and low viability of pancreatic islets after …
Immunomagnetic isolation of islets from the rat pancreas
P Nandigala, TH Chen, C Yang, WH Hsu… - Biotechnology …, 1997 - Wiley Online Library
Islets were selectively isolated from rat pancreatic digests using magnetic microspheres
coated with anti‐islet monoclonal antibodies. The isolation process was optimized as a …
coated with anti‐islet monoclonal antibodies. The isolation process was optimized as a …
Engineering quadrupole magnetic flow sorting for the isolation of pancreatic islets
DJ Kennedy, P Todd, S Logan, M Becker… - Journal of Magnetism …, 2007 - Elsevier
Quadrupole magnetic flow sorting (QMS) is being adapted from the separation of
suspensions of single cells (< 15μm) to the isolation of pancreatic islets (150–350μm) for …
suspensions of single cells (< 15μm) to the isolation of pancreatic islets (150–350μm) for …
Surgical protocol involving the infusion of paramagnetic microparticles for preferential incorporation within porcine islets
MD Rizzari, TM Suszynski, LS Kidder, SA Stein… - Transplantation …, 2010 - Elsevier
INTRODUCTION: Despite significant advances, widespread applicability of islet cell
transplantation remains elusive. Refinement of current islet isolation protocols may improve …
transplantation remains elusive. Refinement of current islet isolation protocols may improve …
Continuous quadrupole magnetic separation of islets during digestion improves purified porcine islet viability
BP Weegman, VS Kumar Sajja… - Journal of Diabetes …, 2016 - Wiley Online Library
Islet transplantation (ITx) is an emerging and promising therapy for patients with
uncontrolled type 1 diabetes. The islet isolation and purification processes require exposure …
uncontrolled type 1 diabetes. The islet isolation and purification processes require exposure …
A comparison of cell transplantation and retroviral gene transfection as tools to study lineage and differentiation in the rat spinal cord
SS McMahon, KW McDermott - Journal of neuroscience methods, 2006 - Elsevier
Establishing the cell lineage relationships of cells during development allows insight into
when and where developmental decisions are made. In the developing spinal cord, the …
when and where developmental decisions are made. In the developing spinal cord, the …