Targeted screening of individuals at high risk for pancreatic cancer: results of a simulation model

PV Pandharipande, C Heberle, EC Dowling, CY Kong… - Radiology, 2015 - pubs.rsna.org
Purpose To identify when, from the standpoint of relative risk, magnetic resonance (MR)
imaging–based screening may be effective in patients with a known or suspected genetic …

Using active learning for speeding up calibration in simulation models

M Cevik, MA Ergun, NK Stout… - Medical Decision …, 2016 - journals.sagepub.com
Background. Most cancer simulation models include unobservable parameters that
determine disease onset and tumor growth. These parameters play an important role in …

[HTML][HTML] Sequentially calibrating a Bayesian microsimulation model to incorporate new information and assumptions

M DeYoreo, CM Rutter, J Ozik, N Collier - BMC Medical Informatics and …, 2022 - Springer
Background Microsimulation models are mathematical models that simulate event histories
for individual members of a population. They are useful for policy decisions because they …

Targeted cancer screening in average-risk individuals

PM Marcus, AN Freedman, MJ Khoury - American journal of preventive …, 2015 - Elsevier
Targeted cancer screening refers to use of disease risk information to identify those most
likely to benefit from screening. Researchers have begun to explore the possibility of refining …

Cost-savings to Medicare from pre-Medicare colorectal cancer screening

SL Goede, KM Kuntz, M Van Ballegooijen… - Medical care, 2015 - journals.lww.com
Background: Many individuals have not received recommended colorectal cancer (CRC)
screening before they become Medicare eligible at the age of 65. We aimed to estimate the …

Validation of colorectal cancer models on long-term outcomes from a randomized controlled trial

M DeYoreo, I Lansdorp-Vogelaar… - Medical Decision …, 2020 - journals.sagepub.com
Microsimulation models are often used to predict long-term outcomes and guide policy
decisions regarding cancer screening. The United Kingdom Flexible Sigmoidoscopy …

The combined use of serum neurotensin and IL-8 as screening markers for colorectal cancer

G Sgourakis, A Papapanagiotou, C Kontovounisios… - Tumor Biology, 2014 - Springer
This pilot study aimed to determine the feasibility of serum neurotensin/IL-8 values being
used as a screening tool for colorectal cancer. Fifty-six patients and 15 healthy controls were …

[HTML][HTML] Detection of postcolonoscopy colorectal neoplasia by multi-target stool DNA

DW Ebner, JD Eckmann, KN Burger… - Clinical and …, 2021 - journals.lww.com
METHODS: In a retrospective cohort of patients with+ mt-sDNA and completed follow-up
colonoscopy, positive predictive value (PPV) for endpoints of any CRN, advanced adenoma …

[HTML][HTML] The role of neurotensin as a novel biomarker in the endoscopic screening of high-risk population for developing colorectal neoplasia

C Kontovounisios, S Qiu, S Rasheed, A Darzi… - Updates in Surgery, 2017 - Springer
Colorectal cancer screening programs aim at early detection of cancer to reduce incidence
rates and mortality. The objective of this study is to identify the role of neurotensin in the …

Risk of colorectal cancer after a negative colonoscopy in low-to-moderate risk individuals: impact of a 10-year colonoscopy

SK Murthy, C Dubé, A Rostom, EI Benchimol… - …, 2017 - thieme-connect.com
Background and study aims National societies recommend colorectal cancer (CRC)
screening 10 years after a normal (“negative”) colonoscopy in low-risk individuals. We …