The role of epigenetics in neuroinflammatory-driven diseases
S Giallongo, L Longhitano, S Denaro… - International Journal of …, 2022 - mdpi.com
Neurodegenerative disorders are characterized by the progressive loss of central and/or
peripheral nervous system neurons. Within this context, neuroinflammation comes up as one …
peripheral nervous system neurons. Within this context, neuroinflammation comes up as one …
Neuroimmune crosstalk between the peripheral and the central immune system in amyotrophic lateral sclerosis
W Yu, J He, X Cai, Z Yu, Z Zou, D Fan - Frontiers in Aging …, 2022 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a fatal disease characterized by the degeneration and
death of motor neurons. Systemic neuroinflammation contributes to the pathogenesis of …
death of motor neurons. Systemic neuroinflammation contributes to the pathogenesis of …
Inflammatory checkpoints in amyotrophic lateral sclerosis: From biomarkers to therapeutic targets
Z Jiang, Z Wang, X Wei, XF Yu - Frontiers in Immunology, 2022 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by
progressive motor neuron damage. Due to the complexity of the ALS, so far the etiology and …
progressive motor neuron damage. Due to the complexity of the ALS, so far the etiology and …
Neuropathogenesis-on-chips for neurodegenerative diseases
S Amartumur, H Nguyen, T Huynh, TS Kim… - Nature …, 2024 - nature.com
Developing diagnostics and treatments for neurodegenerative diseases (NDs) is
challenging due to multifactorial pathogenesis that progresses gradually. Advanced in vitro …
challenging due to multifactorial pathogenesis that progresses gradually. Advanced in vitro …
Molecular hallmarks of ageing in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a fatal, severely debilitating and rapidly progressing
disorder affecting motor neurons in the brain, brainstem, and spinal cord. Unfortunately …
disorder affecting motor neurons in the brain, brainstem, and spinal cord. Unfortunately …
Small molecules targeting different cellular pathologies for the treatment of amyotrophic lateral sclerosis
MF Elmansy, CT Reidl, M Rahaman… - Medicinal Research …, 2023 - Wiley Online Library
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease in which the
motor neuron circuitry displays progressive degeneration, affecting mostly the motor …
motor neuron circuitry displays progressive degeneration, affecting mostly the motor …
Depletion of perivascular macrophages delays ALS disease progression by ameliorating blood-spinal cord barrier impairment in SOD1G93A mice
K Adachi, K Miyata, Y Chida, M Hirose… - Frontiers in Cellular …, 2023 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease in which non-cell-
autonomous processes have been proposed as its cause. Non-neuronal cells that constitute …
autonomous processes have been proposed as its cause. Non-neuronal cells that constitute …
The multifaceted role of GPCRs in amyotrophic lateral sclerosis: a new therapeutic perspective?
Amyotrophic lateral sclerosis (ALS) is a degenerating disease involving the motor neurons,
which causes a progressive loss of movement ability, usually leading to death within 2 to 5 …
which causes a progressive loss of movement ability, usually leading to death within 2 to 5 …
Respiratory pathology in the TDP-43 transgenic mouse model of amyotrophic lateral sclerosis
DD Biswas, R Sethi, Y Woldeyohannes… - Frontiers in …, 2024 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that results
in death within 2–5 years of diagnosis. Respiratory failure is the most common cause of …
in death within 2–5 years of diagnosis. Respiratory failure is the most common cause of …
Intranasal Lipid Nanoparticles Containing Bioactive Compounds Obtained from Marine Sources to Manage Neurodegenerative Diseases
J Torres, I Costa, AF Peixoto, R Silva, JM Sousa Lobo… - Pharmaceuticals, 2023 - mdpi.com
Marine sources contain several bioactive compounds with high therapeutic potential, such
as remarkable antioxidant activity that can reduce oxidative stress related to the …
as remarkable antioxidant activity that can reduce oxidative stress related to the …