The intestinal mucosa provides a selective permeable barrier for nutrient absorption and
protection from external factors. It consists of epithelial cells, immune cells and their …

An enhanced understanding of the importance of Janus kinase (JAK) and signal transducer
and activator of transcription (STAT) signalling in multiple disease states has led to an …

Inflammatory bowel disease (IBD) pathogenesis is associated with gut mucosal
inflammation, epithelial damage, and dysbiosis leading to a dysregulated gut mucosal …

CD28 and CTLA-4 are both important stimulatory receptors for the regulation of T cell
activation. Because receptors share common ligands, B7. 1 and B7. 2, the expression and …

Aberrant activation of NLRP3 inflammasome in colonic macrophages strongly associates
with the occurrence and progression of ulcerative colitis. Although targeting NLRP3 …

Inflammatory bowel disease (IBD) is a debilitating disorder involving inflammation of the
gastrointestinal tract. The incidence of IBD is increasing worldwide. Immunological …

Inflammatory bowel disease (IBD) is a disease caused by a dysregulated immune with
unknown etiology. Hericium erinaceus (H. erinaceus) is a Chinese medicinal fungus, with …

Sophora japonica flower, rich in rutin, is a homology of medicine and food that can be used
as an anti-inflammatory agent. Its effects and mechanisms against intestinal inflammation …

Scope Polyphenol‐enriched herbal extracts have been proved as alternative therapeutic
strategies for experimentally induced colitis. The in vivo and in vitro anti‐inflammatory effects …

Vitamin D (VD) is a pro-hormone that has long been known as a key regulator of calcium
homeostasis and bone health in both children and adults. In recent years, studies have …