[HTML][HTML] Initial antimicrobial management of sepsis

MS Niederman, RM Baron, L Bouadma, T Calandra… - Critical care, 2021 - Springer
Sepsis is a common consequence of infection, associated with a mortality rate> 25%.
Although community-acquired sepsis is more common, hospital-acquired infection is more …

Systematic review of the impact of appropriate versus inappropriate initial antibiotic therapy on outcomes of patients with severe bacterial infections

M Bassetti, J Rello, F Blasi, H Goossens… - International journal of …, 2020 - Elsevier
We investigated the impact of appropriate versus inappropriate initial antimicrobial therapy
on the clinical outcomes of patients with severe bacterial infections as part of a systematic …

Healthcare-associated infections in adult intensive care unit patients: Changes in epidemiology, diagnosis, prevention and contributions of new technologies

S Blot, E Ruppé, S Harbarth, K Asehnoune… - Intensive and Critical …, 2022 - Elsevier
Patients in intensive care units (ICUs) are at high risk for healthcare-acquired infections
(HAI) due to the high prevalence of invasive procedures and devices, induced …

Poor timing and failure of source control are risk factors for mortality in critically ill patients with secondary peritonitis

G De Pascale, M Antonelli, M Deschepper… - Intensive care …, 2022 - Springer
Purpose To describe data on epidemiology, microbiology, clinical characteristics and
outcome of adult patients admitted in the intensive care unit (ICU) with secondary peritonitis …

Myeloid cells in sepsis‐acquired immunodeficiency

F Venet, J Demaret, M Gossez… - Annals of the New York …, 2021 - Wiley Online Library
Abstract On May 2017, the World Health Organization recognized sepsis as a global health
priority. Sepsis profoundly perturbs immune homeostasis by initiating a complex response …

[HTML][HTML] Detrimental effect of ozone on pathogenic bacteria

K Rangel, FO Cabral, GC Lechuga, JPRS Carvalho… - Microorganisms, 2021 - mdpi.com
(1) Background: Disinfection of medical devices designed for clinical use associated or not
with the growing area of tissue engineering is an urgent need. However, traditional …

Rise of the guardians: Gut microbial maneuvers in bacterial infections

U Gupta, P Dey - Life sciences, 2023 - Elsevier
Aims Bacterial infections are one of the major causes of mortality globally. The gut
microbiota, primarily comprised of the commensals, performs an important role in …

Post-operative abdominal infections: epidemiology, operational definitions, and outcomes

M Bassetti, C Eckmann, DR Giacobbe, M Sartelli… - Intensive care …, 2020 - Springer
Postoperative abdominal infections are an important and heterogeneous health challenge in
intensive care units (ICU) and encompass postoperative infectious processes developing …

Epidemiology and age-related mortality in critically ill patients with intra-abdominal infection or sepsis: an international cohort study

K Arvaniti, G Dimopoulos, M Antonelli, K Blot… - International Journal of …, 2022 - Elsevier
Objective To describe epidemiology and age-related mortality in critically ill older adults with
intra-abdominal infection. Methods A secondary analysis was undertaken of a prospective …

Tracking epidemiological characteristics and risk factors of multi-drug resistant bacteria in intensive care units

C Wu, J Lu, L Ruan, J Yao - Infection and Drug Resistance, 2023 - Taylor & Francis
Objectives Multi-drug resistance (MDR) emerged as a serious threat in intensive care unit
(ICU) settings. Our study aimed to investigate the major pathogens in ICU and identify the …