The ability to monitor lymphocyte responses is critical for developing our understanding of
the immune response in humans. In the current clinical setting, relying on the metabolic …

Pertussis, caused by Bordetella (B.) pertussis, a Gram-negative bacterium, is a highly
contagious airway infection. Especially in infants, pertussis remains a major health concern …

Adoptive therapy with regulatory T cells or tolerance-inducing antigen (Ag)-presenting cells
is innovative and promising therapeutic approach to control undesired and harmful …

To better understand vaccine-induced protection and its potential failure in light of recent
whooping cough resurgence, we evaluated quantity as well as quality of memory T cell …

Based on current studies on the effects of single dose vaccines on antibody production,
Latin American countries have adopted a single dose vaccine program. However, no data …

In 2005, in accordance with recommendations made by the European Medicines Agency,
the Italian Drug Agency ordered withdrawal of the hexavalent Hexavac® vaccine (Sanofi …

Biobanking is an operational component of various epidemiological studies and clinical
trials. Although peripheral blood is routinely acquired and stored in biobanks, the effects of …

Pertussis ('whooping cough') is a severe respiratory tract infection that primarily affects
young children and unimmunised infants. Despite widespread vaccine coverage, it remains …

Introduction Maternal antibody interference of the infant's humoral immune responses raises
some concern to the strategy of maternal Tdap (tetanus, diphtheria, acellular pertussis [aP]) …

While it is clear that the maintenance of Bordetella pertussis-specific immunity evoked both
after vaccination and infection is insufficient, it is unknown at which pace waning occurs and …