Calcium ion (Ca 2+) is a ubiquitous and versatile signaling molecule controlling a wide
variety of cellular processes, such as proliferation, cell death, migration, and immune …

Cardiac arrhythmias are among the leading causes of mortality. They often arise from
alterations in the electrophysiological properties of cardiac cells and their underlying ionic …

The function of a cell is defined by its intrinsic characteristics and its niche: the tissue
microenvironment in which it dwells. Here we combine single-cell and spatial …

The human gut is colonized by a community of microbiota, primarily bacteria, that exist in a
symbiotic relationship with the host. Intestinal microbiota-host interactions play a critical role …

In this focused update, the American Heart Association provides updated guidance for
resuscitation of patients with cardiac arrest, respiratory arrest, and refractory shock due to …

Brugada syndrome (BrS) is an “inherited” condition characterized by predisposition to
syncope and cardiac arrest, predominantly during sleep. The prevalence is∼ 1: 2,000, and …

Cardiovascular drugs and lipid regulating agents have emerged as major groups of
environmental contaminants over the past decades. However, knowledge about their …

Intracellular calcium signaling is a universal language source shared by the most part of
biological entities inside cells that, all together, give rise to physiological and functional …

Polymorphic ventricular tachyarrhythmias are highly lethal arrhythmias. Several types of
polymorphic ventricular tachycardia have similar electrocardiographic characteristics but …

Barth syndrome is a rare X-linked genetic disease classically characterized by
cardiomyopathy, skeletal myopathy, growth retardation, neutropenia, and 3 …