Sleep apnea: types, mechanisms, and clinical cardiovascular consequences

S Javaheri, F Barbe, F Campos-Rodriguez… - Journal of the American …, 2017 - jacc.org
Sleep apnea is highly prevalent in patients with cardiovascular disease. These disordered
breathing events are associated with a profile of perturbations that include intermittent …

Oxidative stress and inflammation in the evolution of heart failure: from pathophysiology to therapeutic strategies

A Aimo, V Castiglione, C Borrelli… - European journal of …, 2020 - journals.sagepub.com
Both oxidative stress and inflammation are enhanced in chronic heart failure. Dysfunction of
cardiac mitochondria is a hallmark of heart failure and a leading cause of oxidative stress …

Device Therapy in Chronic Heart Failure: JACC State-of-the-Art Review

M Fudim, WT Abraham, RS von Bardeleben… - Journal of the American …, 2021 - jacc.org
The regulatory landscape for device-based heart failure (HF) therapies has seen a major
shift in the last 7 years. In 2013, the US Food and Drug Administration released guidance for …

Prevalence and predictors of sleep-disordered breathing in patients with stable chronic heart failure: the SchlaHF registry

M Arzt, H Woehrle, O Oldenburg, A Graml, A Suling… - JACC: Heart Failure, 2016 - jacc.org
Objectives: This prospective study investigated the prevalence of sleep-disordered
breathing (SDB) and its predictors in patients with stable chronic heart failure (HF) …

Transvenous neurostimulation for central sleep apnoea: a randomised controlled trial

MR Costanzo, P Ponikowski, S Javaheri, R Augostini… - The Lancet, 2016 - thelancet.com
Background Central sleep apnoea is a serious breathing disorder associated with poor
outcomes. The remedé system (Respicardia Inc, Minnetonka, MN, USA) is an implantable …

Heart failure and sleep disorders

G Parati, C Lombardi, F Castagna… - Nature Reviews …, 2016 - nature.com
Awareness of the importance of sleep-related disorders in patients with cardiovascular
diseases is growing. In particular, sleep-disordered breathing, short sleep time, and low …

Diagnosis, management and pathophysiology of central sleep apnea in children

AT McLaren, S Bin-Hasan, I Narang - Paediatric respiratory reviews, 2019 - Elsevier
Central sleep apnea (CSA) is thought to occur in about 1–5% of healthy children. CSA
occurs more commonly in children with underlying disease and the presence of CSA may …

Phrenic nerve stimulation to treat patients with central sleep apnoea and heart failure

MR Costanzo, P Ponikowski, A Coats… - European Journal of …, 2018 - Wiley Online Library
Aims The presence of central sleep apnoea (CSA) is associated with poor prognosis in
patients with heart failure (HF). The aim of this analysis was to evaluate if using phrenic …

[PDF][PDF] Common sleep disorders affecting older adults

EE Jaqua, M Hanna, W Labib… - The Permanente …, 2023 - thepermanentejournal.org
Sleep disorders in older adults increase with aging, likely due to increased sleep latency,
decreased sleep efficiency, and total sleep time. Common sleep issues include chronic …

Prognostic significance of central apneas throughout a 24-hour period in patients with heart failure

M Emdin, G Mirizzi, A Giannoni, R Poletti… - Journal of the American …, 2017 - jacc.org
Background: Large trials using noninvasive mechanical ventilation to treat central apnea
(CA) occurring at night (“sleep apnea”) in patients with systolic heart failure (HF) have failed …