Tailoring oral anticoagulant treatment in the era of multi-drug therapies for PAH and CTEPH

J Escal, G Poenou, X Delavenne, S Bezzeghoud… - Blood Reviews, 2024 - Elsevier
The use of oral anticoagulants in the management of pulmonary arterial hypertension (PAH)
and chronic thromboembolic pulmonary hypertension (CTEPH) presents distinct therapeutic …

Managing Drug-Drug Interactions—So Many Drugs, So Little Evidence

HB Mehta, GC Alexander - JAMA Network Open, 2024 - jamanetwork.com
We are fortunate to live in an era with an expansive pharmacopeia, and more than 20 000
prescription drug products are currently approved by the US Food and Drug Administration …

Bleeding in Patients With Atrial Fibrillation—Reply

WA Ray, CM Stein, KT Murray - JAMA, 2024 - jamanetwork.com
In Reply Although the available data suggest that, in patients with atrial fibrillation, sex is not
associated with serious oral anticoagulant-related bleeding, 1 as suggested by Dr …

Diltiazem, direct oral anticoagulants, and risk of major bleeding in patients with atrial fibrillation

SP Ang, C Krittanawong, JE Chia, S Patel… - Heart …, 2024 - heartrhythmjournal.com
Direct oral anticoagulants (DOACs) are the preferred anticoagulant strategy for stroke
prevention in patients with atrial fibrillation (AF). Concomitantly, non-dihydropyridine (non …

Bleeding in Patients With Atrial Fibrillation

BTS Bannow, A Colwill, A Edelman - JAMA, 2024 - jamanetwork.com
To the Editor A recent study1 reported a higher incidence of serious bleeding in patients
using diltiazem, compared with metoprolol, in conjunction with apixaban or rivaroxaban for …

[HTML][HTML] Potential interactions between medications for rate control and direct oral anticoagulants: population-based cohort and case-crossover study

AYS Wong, C Warren-Gash, K Bhaskaran, C Leyrat… - Heart Rhythm, 2024 - Elsevier
Abstract Background Direct oral anticoagulants (DOACs) are commonly co-prescribed with
amiodarone/diltiazem/verapamil, but whether there is a drug interaction between these …

Do Non-Dihydropyridine Calcium Channel Blockers Increase Bleeding Risk with Direct Oral Anticoagulants?

P Calvert, GYH Lip - Heart Rhythm, 2024 - Elsevier
Drug interactions are not a new phenomenon, yet some may be overlooked simply because
they are not well recognised. Recent studies have highlighted an interaction between …

Redaktørens hjørne# 65: Kunstig intelligens og kreft, hjertehelse, menneskehetens grandtante

J Didriksen - Tidsskrift for Den norske legeforening, 2024 - tidsskriftet.no
Forskere har sett på dødeligheten hos fanger løslatt fra fengsel (1, 2). Hvor effektivt er det å
bruke kunstig intelligens til å bistå ved diagnostisering av kreft (3, 4)? I en dansk studie har …