Lipid nanoparticles for the posterior eye segment

L Bonilla, M Espina, P Severino, A Cano, M Ettcheto… - Pharmaceutics, 2021 - mdpi.com
This review highlights the application of lipid nanoparticles (Solid Lipid Nanoparticles,
Nanostructured Lipid Carriers, or Lipid Drug Conjugates) as effective drug carriers for …

Challenges and strategies for ocular posterior diseases therapy via non-invasive advanced drug delivery

Q Qi, Y Wei, X Zhang, J Guan, S Mao - Journal of Controlled Release, 2023 - Elsevier
Posterior segment diseases, such as age-related macular degeneration (AMD) and diabetic
retinopathy (DR) are vital factor that seriously threatens human vision health and quality of …

Functional chitosan oligosaccharide nanomicelles for topical ocular drug delivery of dexamethasone

X Xu, L Sun, L Zhou, Y Cheng, F Cao - Carbohydrate polymers, 2020 - Elsevier
Chitosan oligosaccharide-valylvaline-stearic acid (CSO-VV-SA) nanomicelles were
designed for topical ocular drug delivery, based on peptide transporter-1 (PepT-1) active …

Trimethylated chitosan-coated flexible liposomes with resveratrol for topical drug delivery to reduce blue-light-induced retinal damage

H Gu, P Chen, X Liu, Y Lian, J Xi, J Li, J Song… - International Journal of …, 2023 - Elsevier
LED-related blue-light-induced damage can cause eye diseases. However, drug delivery in
patients with ocular diseases is faced with various challenges. In this study, we developed …

Connecting the dots in drug delivery: a tour d'horizon of chitosan-based nanocarriers system

S Pramanik, V Sali - International Journal of Biological Macromolecules, 2021 - Elsevier
One of the most promising pharmaceutical research areas is developing advanced delivery
systems for controlled and sustained drug release. The drug delivery system (DDS) can be …

A review of nanocarrier-mediated drug delivery systems for posterior segment eye disease: Challenges analysis and recent advances

R Wang, Y Gao, A Liu, G Zhai - Journal of drug targeting, 2021 - Taylor & Francis
Posterior segment eye disease is a leading cause of irreversible vision impairment and
blindness. As the unique organ for vision, eyes are protected by various protective barriers …

Microneedle scleral patch for minimally invasive delivery of triamcinolone to the posterior segment of eye

G Roy, P Garg, VVK Venuganti - International Journal of Pharmaceutics, 2022 - Elsevier
The delivery of therapeutics to the posterior segment of the eye is achieved by invasive
procedures, including intravitreal injections and implants. The topically applied formulations …

Posterior segment ophthalmic drug delivery: Role of muco-adhesion with a special focus on chitosan

AM Burhan, B Klahan, W Cummins, V Andrés-Guerrero… - Pharmaceutics, 2021 - mdpi.com
Posterior segment eye diseases (PSEDs) including age macular degeneration (AMD) and
diabetic retinopathy (DR) are amongst the major causes of irreversible blindness worldwide …

Advanced vesicular systems for antifungal drug delivery

S Mosallam, R Albash, MA Abdelbari - AAPS PharmSciTech, 2022 - Springer
Fungal infections are considered one of the most serious conditions as their occurrence has
increased lately. Fungi like Candida, Fusarium, and Aspergillus species mostly affect …

Multifunctional carboxymethyl chitosan derivatives-layered double hydroxide hybrid nanocomposites for efficient drug delivery to the posterior segment of the eye

Y Wang, L Zhou, L Fang, F Cao - Acta biomaterialia, 2020 - Elsevier
Efficient ocular drug delivery to the posterior segment of the eye by topical administration is
a great challenge to pharmacologists. To explore drug delivery system of organic-inorganic …