The development of Pharmacogenetics and Pharmacogenomics in Western Europe is
highly relevant in the worldwide scenario. Despite the usually low institutional support, many …

The determination of antidepressant drugs which act by blocking neuronal uptake of
biogenic amines, because of their widespread use and high toxicity, remains one of the most …

Therapeutic drug monitoring (TDM) is a valuable tool for tailoring the dosage of the
prescribed medication (s) to the individual pharmacokinetic characteristics of a patient. In …

A reversed-phase high performance liquid chromatography (HPLC) method for the
determination of plasma and serum levels of amitriptyline (AMI), nortriptyline (NORT) …

Extracted from the Drug Abuse Handbook, 2nd edition, to give you just the information you
need at an affordable price. Postmortem Toxicology of Abused Drugs considers the role of …

Ingestion of toxic substances is a common problem in pediatrics. When presented with the
limited history of an unknown ingestion in a patient with altered mental status, a clinician …

Quetiapine is an atypical antipsychotic agent with structural similarities to the tricyclic
antidepressants (TCA). We report a case of quetiapine overdose that was initially clinically …

For drugs with a narrow therapeutic index, therapeutic drug monitoring methods are
essential for patient management. Although immunoassays are commercially available for …

A fast and easy solid-phase extraction method was developed for the determination of
amitriptyline, doxepin and their metabolites (nortriptyline and nordoxepin) in porcine serum …

A fast kinetic method is proposed for the photometric and fluorimetric determination of
nortriptyline hydrochloride. The method involves measuring the rate of formation of an …