Anticancer and reversing multidrug resistance activities of natural isoquinoline alkaloids and their structure-activity relationship

ZX Qing, JL Huang, XY Yang, JH Liu… - Current medicinal …, 2018 - ingentaconnect.com
The severe anticancer situation as well as the emergence of multidrug-resistant (MDR)
cancer cells has created an urgent need for the development of novel anticancer drugs with …

Isoquinoline alkaloids and their antiviral, antibacterial, and antifungal activities and structure-activity relationship

ZX Qing, P Yang, Q Tang, P Cheng… - Current Organic …, 2017 - ingentaconnect.com
Background & Objective: The emergence of multidrug-resistant virus, bacteria and fungi has
created an urgent need for the development of novel antibiotic drugs from natural products …

Effects of Dietary Macleaya cordata Extract Containing Isoquinoline Alkaloids Supplementation as an Alternative to Antibiotics in the Diets on Growth Performance …

Y Liu, Y Li, J Niu, H Liu, N Jiao, L Huang… - Frontiers in Veterinary …, 2022 - frontiersin.org
This study aimed to investigate the effects of dietary supplementation with Macleaya cordata
extract (MCE) containing protopine and allotypotopine on the growth performance and liver …

[HTML][HTML] Neuroprotective effects of allocryptopine-rich alkaloid extracts against oxidative stress-induced neuronal damage

SN Dolanbay, FG Kocanci, B Aslim - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Background Oxidative stress is a significant feature in the pathomechanism of
neurodegenerative diseases. Thus, the search for an effective and safe novel antioxidant …

[HTML][HTML] Role of plant derived alkaloids as antioxidant agents for neurodegenerative diseases

S Sirin, SN Dolanbay, B Aslim - Health Sciences Review, 2023 - Elsevier
Neurodegenerative diseases (NDs) encompass a broad range of conditions characterized
by progressive neuronal degeneration and death and manifesting with a variety of signs and …

Cholinesterase and Prolyl Oligopeptidase Inhibitory Activities of Alkaloids from Argemone platyceras (Papaveraceae)

T Siatka, M Adamcová, L Opletal, L Cahlíková, D Jun… - Molecules, 2017 - mdpi.com
Alzheimer's disease is an age-related, neurodegenerative disorder, characterized by
cognitive impairment and restrictions in activities of daily living. This disease is the most …

Alkaloids as potential multi-target drugs to treat Alzheimer's disease

JA Lima, L Hamerski - Studies in natural products chemistry, 2019 - Elsevier
Neurodegenerative diseases are characterized by the progressive and irreversible loss of
neurons from specific regions of the brain. The pattern of neuronal loss is selective, affecting …

Modulatory Effects of Eschscholzia californica Alkaloids on Recombinant GABAA Receptors

M Fedurco, J Gregorová, K Šebrlová… - Biochemistry …, 2015 - Wiley Online Library
The California poppy (Eschscholzia californica Cham.) contains a variety of natural
compounds including several alkaloids found exclusively in this plant. Because of the …

Anti-inflammatory, anti-bacterial and anti-acetylcholinesterase activities of two isoquinoline alkaloids–Scoulerine and Cheilanthifoline

P Wangchuk, T Sastraruji… - Natural product …, 2016 - journals.sagepub.com
Corydalis plants containing isoquinoline alkaloids are reported to possess promising
pharmacological properties for the treatment of important diseases including cancer …

Phytochemistry and pharmacology of alkaloids from Glaucium spp.

T Akaberi, K Shourgashti, SA Emami, M Akaberi - Phytochemistry, 2021 - Elsevier
Glaucium Mill. comprising 28 species with 78 synonyms, 3 subspecies, and 3 varieties
worldwide belongs to the Papaveraceae family. The plants are well known for their different …