Biological rhythm and chronotype: new perspectives in health
The circadian rhythm plays a fundamental role in regulating biological functions, including
sleep–wake preference, body temperature, hormonal secretion, food intake, and cognitive …
sleep–wake preference, body temperature, hormonal secretion, food intake, and cognitive …
Adipokines: new potential therapeutic target for obesity and metabolic, rheumatic, and cardiovascular diseases
L Recinella, G Orlando, C Ferrante… - Frontiers in …, 2020 - frontiersin.org
Besides its role as an energy storage organ, adipose tissue can be viewed as a dynamic
and complex endocrine organ, which produces and secretes several adipokines, including …
and complex endocrine organ, which produces and secretes several adipokines, including …
Reasons for and consequences of low energy availability in female and male athletes: social environment, adaptations, and prevention
Low energy availability (LEA) represents a state in which the body does not have enough
energy left to support all physiological functions needed to maintain optimal health. When …
energy left to support all physiological functions needed to maintain optimal health. When …
Targeting adipose tissue in the treatment of obesity-associated diabetes
CM Kusminski, PE Bickel, PE Scherer - Nature reviews Drug discovery, 2016 - nature.com
Adipose tissue regulates numerous physiological processes, and its dysfunction in obese
humans is associated with disrupted metabolic homeostasis, insulin resistance and type 2 …
humans is associated with disrupted metabolic homeostasis, insulin resistance and type 2 …
Pubertal development and regulation
Puberty marks the end of childhood and is a period when individuals undergo physiological
and psychological changes to achieve sexual maturation and fertility. The hypothalamic …
and psychological changes to achieve sexual maturation and fertility. The hypothalamic …
Obesity and leptin resistance: distinguishing cause from effect
Because leptin reduces food intake and body weight, the coexistence of elevated leptin
levels with obesity is widely interpreted as evidence of 'leptin resistance.'Indeed, obesity …
levels with obesity is widely interpreted as evidence of 'leptin resistance.'Indeed, obesity …
Brief communication: sleep curtailment in healthy young men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetite
K Spiegel, E Tasali, P Penev… - Annals of internal …, 2004 - acpjournals.org
Background: Total sleep deprivation in rodents and in humans has been associated with
hyperphagia. Over the past 40 years, self-reported sleep duration in the United States has …
hyperphagia. Over the past 40 years, self-reported sleep duration in the United States has …
Interactions between sleep, circadian function, and glucose metabolism: implications for risk and severity of diabetes
S Reutrakul, E Van Cauter - Annals of the New York Academy …, 2014 - Wiley Online Library
Sleep disturbances, including sleep insufficiency and sleep fragmentation, have been linked
to abnormal glucose metabolism and increased diabetes risk. Well‐controlled laboratory …
to abnormal glucose metabolism and increased diabetes risk. Well‐controlled laboratory …
[HTML][HTML] The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis
The gastrointestinal peptide hormone ghrelin stimulates appetite in rodents and humans via
hypothalamic actions. We discovered expression of ghrelin in a previously uncharacterized …
hypothalamic actions. We discovered expression of ghrelin in a previously uncharacterized …
Physiological role of adipose tissue: white adipose tissue as an endocrine and secretory organ
P Trayhurn, JH Beattie - Proceedings of the Nutrition Society, 2001 - cambridge.org
The traditional role attributed to white adipose tissue is energy storage, fatty acids being
released when fuel is required. The metabolic role of white fat is, however, complex. For …
released when fuel is required. The metabolic role of white fat is, however, complex. For …