Activated fibroblasts in tumors, or cancer-associated fibroblasts (CAFs), have become a
popular research area over the past decade. As important players in many aspects of tumor …

Glycosaminoglycans (GAGs) are an important component of the extracellular matrix as they
influence cell behavior and have been sought for tissue regeneration, biomaterials, and …

Globally, millions of people suffer from poor wound healing, which is associated with higher
mortality rates and higher healthcare costs. There are several factors that can complicate the …

Medical dressings play an important role in the field of tissue engineering owing to their
ability to accelerate the process of wound healing. Great efforts have been made to fabricate …

New topical antibacterial agents are required to inhibit and development of bacteria and
also promoting the wound healing process. This study was evaluating the healing effect of …

The development of targeted therapies for wound repair is knowing a growing interest due to
the increasing aging of the population and the incidence of chronic pathologies, mainly …

Effective treatment strategies for skin wound repair are the focus of numerous studies. New
pharmacological approaches appear necessary to guarantee a correct and healthy tissue …

Abstract Hypoxia-inducible factor-1 alpha (HIF-1α) is usually regarded as a core regulator of
hypoxic response. Persistent inflammation and impaired wound healing are common …

Antibacterial multilayer electrospun matrices based on hyaluronic acid (HA) and a lactose-
modified chitosan (CTL) were synthetized (i) by combining electrospun polycaprolactone …

Healing chronic diabetic wounds is challenging because of excessive reactive oxygen
species (ROS) and hypoxia in the wound microenvironment. To address this issue, we …