Since their inception, rhodamine dyes have been extensively applied in biotechnology as
fluorescent markers or for the detection of biomolecules owing to their good optical physical …

Serving as the basis of cell life, interactions between nucleic acids and proteins play
essential roles in fundamental cellular processes. Aptamers are unique single-stranded …

In addition to critical biological roles, DNA is also considered an excellent engineering
material with unique characteristics of high programmability and addressability. Recent …

Progress with fluorescent flippers, small-molecule probes to image membrane tension in
living systems, has been limited by the effort needed to synthesize the twisted push–pull …

Aptamers have been spotlighted as promising bio-recognition elements because they can
be tailored to specific target molecules, bind to targets with a high affinity and specificity, and …

Early and rapid diagnosis of tumors is essential for clinical treatment or management. In
contrast to conventional means, bioimaging has the potential to accurately locate and …

Extracellular pH plays vital roles in physiological and pathological processes including
tumor metastasis and chemotherapy resistance. Abnormal extracellular pH is known to be …

Molecular imaging is a non‐invasive imaging method that is widely used for visualization
and detection of biological events at cellular or molecular levels. Stimuli‐responsive linkers …

Aptamers are typically defined as relatively short (20–60 nucleotides) single-stranded DNA
or RNA molecules that bind with high affinity and specificity to various types of targets …

Background As the most common subtype in lung cancer, the precise and efficient treatment
for non-small cell lung cancer (NSCLC) remains an outstanding challenge owing to early …