Pairwise meta‐analysis is an established statistical tool for synthesizing evidence from
multiple trials, but it is informative only about the relative efficacy of two specific …

Randomized trials may be designed and interpreted as single experiments or they may be
seen in the context of other similar or relevant evidence. The amount and complexity of …

Background Economic evaluations of health interventions pose a particular challenge for
reporting because substantial information must be conveyed to allow scrutiny of study …

Opioid-related overdose deaths have increased since 2010 in the US, but information on
trends in opioid use disorder (OUD) prevalence is limited due to unreliable data. Multiplier …

In this paper, we formalize the application of multivariate meta‐analysis and meta‐
regression to synthesize estimates of multi‐parameter associations obtained from different …

The third volume in the Handbooks in Health Economic Evaluation series, this book
provides the reader with a comprehensive set of instructions and examples of how to …

A practical guide to network meta-analysis with examples and code In the evaluation of
healthcare, rigorous methods of quantitative assessment are necessary to establish which …

Objectives To determine the effects of low-to-moderate levels of maternal alcohol
consumption in pregnancy on pregnancy and longer-term offspring outcomes. Search …

The art and science of meta‐analysis, the combination of results from multiple independent
studies, is now more than a century old. In the last 30 years, however, as the need for …

That the published scientific literature documents only a proportion of the results of all
research carried out is a perpetual concern. Further, there is good direct and indirect …