NADH peroxidase (Npx) and mercuric ion reductase (MerA) are flavoproteins belonging to
the pyridine nucleotide: disulfide oxidoreductases (PNDO) and catalyzing the reduction of …

Six charged amino acid residues located in the ectodomain of the full-length type I
transforming growth factor (TGF)-β receptor were individually mutated to alanine. Mutation of …

The α subunit of bacterial luciferase unfolds and refolds reversibly by a three-state
mechanism in urea-containing buffer. It has been proposed that the three-state unfolding of …

This work aimed at identifying essential residues on the α subunit of Vibrio harveyi luciferase
and elucidating their functional roles. Four conserved α-subunit residues at the proposed …

В работе приведены данные исследования влияния катионов К+, Na+, Mg2+ и Ca2+ на
активность биолюминисцентной реакции in vitro и in vivo с определением соотношений …

The bacterial alkanesulfonate monooxygenase system is a two-component enzyme system
involved in the desulfonation of alkanesulfonates when bacteria are starved for sulfur. This …

We employ replica-exchange molecular dynamics (REMD) and a hybrid ab-initio
multiconfigurational quantum mechanics/molecular mechanics (QM/MM) approach to model …

Effect of pH and salinity on the growth and luminescence of a marine bacterium as an
environmental biosensor Resumen El trabajo se desarrolló en el Centro de Estudios de …

To structural biochemists, the three-dimensional structure of the enzyme showing
comprehensive ligand-protein binding interactions is extremely helpful in determining the …

This thesis emphasizes mechanism elucidation and structure-based drug design for multiple
biological systems. Three main topics investigated are:(1) determining the origin of product …