Circulating tumour cells for early detection of clinically relevant cancer

R Lawrence, M Watters, CR Davies, K Pantel… - Nature Reviews Clinical …, 2023 - nature.com
Given that cancer mortality is usually a result of late diagnosis, efforts in the field of early
detection are paramount to reducing cancer-related deaths and improving patient outcomes …

miRNAs as potential game-changers in bone diseases: Future medicinal and clinical Uses

AS Doghish, MS Elballal, O Elazazy… - … -Research and Practice, 2023 - Elsevier
Abstract MicroRNAs (miRNAs), short, highly conserved non-coding RNA, influence gene
expression by sequential mechanisms such as mRNA breakdown or translational …

miRNAs as potential game-changers in retinoblastoma: Future clinical and medicinal uses

AS Doghish, HAM Moustafa, MS Elballal… - … -Research and Practice, 2023 - Elsevier
Retinoblastoma (RB) is a rare tumor in children, but it is the most common primitive
intraocular malignancy in childhood age, especially those below three years old. The RB …

Ferroptosis in lung cancer: a novel pathway regulating cell death and a promising target for drug therapy

N Xing, Q Du, S Guo, G Xiang, Y Zhang, X Meng… - Cell Death …, 2023 - nature.com
Lung cancer is a common malignant tumor that occurs in the human body and poses a
serious threat to human health and quality of life. The existing treatment methods mainly …

Comparative Insight into Microglia/Macrophages-Associated Pathways in Glioblastoma and Alzheimer's Disease

J Shi, S Huang - International Journal of Molecular Sciences, 2023 - mdpi.com
Microglia and macrophages are pivotal to the brain's innate immune response and have
garnered considerable attention in the context of glioblastoma (GBM) and Alzheimer's …

Has-miR-129-5p's involvement in different disorders, from digestive cancer to neurodegenerative diseases

A Boicean, S Birsan, C Ichim, I Boeras, I Roman-Filip… - Biomedicines, 2023 - mdpi.com
At present, it is necessary to identify specific biochemical, molecular, and genetic markers
that can reliably aid in screening digestive cancer and correlate with the degree of disease …

Sickle cell disease update: new treatments and challenging nutritional interventions

V Bell, T Varzakas, T Psaltopoulou, T Fernandes - Nutrients, 2024 - mdpi.com
Sickle cell disease (SCD), a distinctive and often overlooked illness in the 21st century, is a
congenital blood disorder characterized by considerable phenotypic diversity. It comprises a …

Unraveling the role of miRNAs in the diagnosis, progression, and therapeutic intervention of Parkinson's disease

OA Mohammed, MS Elballal, AA El-Husseiny… - … -Research and Practice, 2023 - Elsevier
Parkinson's disease (PD) is a debilitating neurological disorder characterized by the
impairment of the motor system, resulting in symptoms such as resting tremor, cogwheel …

Non-coding RNAs in human cancer and other diseases: overview of the diagnostic potential

R Beňačka, D Szabóová, Z Guľašová… - International journal of …, 2023 - mdpi.com
Non-coding RNAs (ncRNAs) are abundant single-stranded RNA molecules in human cells,
involved in various cellular processes ranging from DNA replication and mRNA translation …

[HTML][HTML] miR-214-3p promotes the pathogenesis of Parkinson's disease by inhibiting autophagy

H Dong, J Yan, P Huang, X Wang, R Zhang… - Biomedicine & …, 2024 - Elsevier
Parkinson's disease (PD) is a prevalent neurodegenerative disorder characterized by
dopaminergic neuron death in the substantia nigra, leading to motor dysfunction. Autophagy …