Chordoma: current status, problems, and future directions
MF Wedekind, BC Widemann, G Cote - Current Problems in Cancer, 2021 - Elsevier
Chordoma is a rare tumor that occurs along the axial spine in pediatrics and adults, with an
incidence of approximately 350 cases per year in the United States. While typically …
incidence of approximately 350 cases per year in the United States. While typically …
The potential role of miR‐1290 in cancer progression, diagnosis, prognosis, and treatment: An oncomiR or onco‐suppressor microRNA?
Cancer is one of the leading causes of death in humans because of the lack of early
diagnosis, distant metastases, and the resistance to adjuvant therapies, including …
diagnosis, distant metastases, and the resistance to adjuvant therapies, including …
Personalized chordoma organoids for drug discovery studies
A Al Shihabi, A Davarifar, HTL Nguyen, N Tavanaie… - Science …, 2022 - science.org
Chordomas are rare tumors of notochordal origin, most commonly arising in the sacrum or
skull base. Chordomas are considered insensitive to conventional chemotherapy, and their …
skull base. Chordomas are considered insensitive to conventional chemotherapy, and their …
DNA methylation-based prognostic subtypes of chordoma tumors in tissue and plasma
JA Zuccato, V Patil, S Mansouri, JC Liu… - Neuro …, 2022 - academic.oup.com
Background Chordomas are rare malignant bone cancers of the skull-base and spine.
Patient survival is variable and not reliably predicted using clinical factors or molecular …
Patient survival is variable and not reliably predicted using clinical factors or molecular …
[HTML][HTML] B7-H3 as a target for CAR-T cell therapy in skull base chordoma
C Long, G Li, C Zhang, T Jiang, Y Li, X Duan… - Frontiers in …, 2021 - frontiersin.org
Objective: chordomas are rare bone tumors with few therapeutic options. Skull base and
sacrum are the two most common origin sites. Immunotherapies are emerging as the most …
sacrum are the two most common origin sites. Immunotherapies are emerging as the most …
[HTML][HTML] Trends in tumor site-specific survival of bone sarcomas from 1980 to 2018: a surveillance, epidemiology and end results-based study
X Hu, K Deng, H Ye, Z Sun, W Huang, Y Sun, W Yan - Cancers, 2021 - mdpi.com
Simple Summary Bone sarcomas are rare cancers coming from the mesenchyme cells of the
body skeletal system. Osteosarcoma, chondrosarcoma, Ewing sarcoma, and chordoma are …
body skeletal system. Osteosarcoma, chondrosarcoma, Ewing sarcoma, and chordoma are …
Targeted delivery of cancer drug paclitaxel to chordomas tumor cells via an RNA nanoparticle harboring an EGFR aptamer
Paclitaxel has been extensively used in clinics for cancer treatment. However, its limited
solubility in aqueous solution and high occurrence of side effects have also been widely …
solubility in aqueous solution and high occurrence of side effects have also been widely …
Chordomas: a review with emphasis on their pathophysiology, pathology, molecular biology, and genetics
G Karpathiou, JM Dumollard, M Dridi, P Dal Col… - … -Research and Practice, 2020 - Elsevier
Chordomas are uncommon, bone, axial, or (rarely) extra-axial tumors that are malignant and
frequently recur but less commonly metastasize. They usually affect adults, with a very small …
frequently recur but less commonly metastasize. They usually affect adults, with a very small …
[HTML][HTML] Chordoma: A Comprehensive Systematic Review of Clinical Trials
S Chen, R Ulloa, J Soffer, RJ Alcazar-Felix… - Cancers, 2023 - mdpi.com
Simple Summary Surgery is the primary treatment for chordoma. However, residual or
recurrent chordoma presents a significant problem for clinicians. The aim of this work is to …
recurrent chordoma presents a significant problem for clinicians. The aim of this work is to …
[HTML][HTML] Multivariate analysis and validation of the prognostic factors for skull base chordoma
Background: Skull base chordoma is a rare tumor with low-grade malignancy and a high
recurrence rate, the factors affecting the prognosis of patients need to be further studied. For …
recurrence rate, the factors affecting the prognosis of patients need to be further studied. For …