Recently, genome-wide association studies have implicated the human LIN28B locus in
regulating height and the timing of menarche,,,,. LIN28B and its homolog LIN28A are …

To determine the incidence and relative risk (RR) of cancer in children with Beckwith-
Wiedemann syndrome (BWS), children with BWS were followed up from birth until death …

OBJECTIVE: To review currently available literature on the association between imprinting
disorders (Beckwith-Wiedemann syndrome [BWS], Angelman syndrome [AS] and …

Wilms tumour has been reported in association with over 50 different clinical conditions and
several abnormal constitutional karyotypes. Conclusive evidence of an increased risk of …

Beckwith–Wiedemann syndrome (BWS) presents with visceromegaly, macroglossia, tumor
predisposition and other congenital abnormalities, and is usually associated with …

Dunne, Mark J., Karen E. Cosgrove, Ruth M. Shepherd, Albert Aynsley-Green, and Keith J.
Lindley. Hyperinsulinism in Infancy: From Basic Science to Clinical Disease. Physiol Rev 84 …

Beckwith–Wiedemann syndrome (BWS) is a clinically heterogeneous overgrowth syndrome
associated with an increased risk for embryonal tumor development. BWS provides an ideal …

In mice, the imprinted Igf2 gene (expressed from the paternal allele), which encodes a
growth-promoting factor (IGF-II), is linked closely to the reciprocally imprinted H19 locus on …

Overgrowth syndromes (OGS) comprise a heterogeneous group of disorders in which the
main characteristic is that either weight, height, or head circumference is 2–3 standard …

Background: Beckwith-Wiedemann syndrome (BWS) is an overgrowth syndrome associated
with an increased risk of pediatric tumors. The underlying molecular abnormalities may be …