Abstract Beckwith–Wiedemann syndrome (BWS), a human genomic imprinting disorder, is
characterized by phenotypic variability that might include overgrowth, macroglossia …

Imprinting disorders (ImpDis) are a group of currently 12 congenital diseases with common
underlying (epi) genetic etiologies and overlapping clinical features affecting growth …

Pancreatic neoplasms are rare in children and have a different histologic spectrum and
prognosis than those in adults. In general, these tumors are well demarcated with expansile …

Genomic imprinting is an epigenetic phenomenon that leads to parent-specific differential
expression of a subset of genes. Most imprinted genes form clusters, or imprinting domains …

Precise control of cell‐cycle progression is believed to be critical for normal development,
while oncogenesis may be a direct result of its disturbance. Cell‐cycle progression is …

Silver–Russell syndrome (SRS MIM180860) is a disorder characterised by intrauterine
and/or postnatal growth restriction and typical facies. However, the clinical picture is …

BACKGROUND Genomic imprinting is an epigenetic process in which allele-specific gene
expression is dependent on the parental inheritance. Although only a minority of human …

Macroglossia, prenatal or postnatal overgrowth, and abdominal wall defects (omphalocele,
umbilical hernia, or diastasis recti) permit early recognition of Beckwith-Wiedemann …

Beckwith–Wiedemann syndrome (BWS) is an overgrowth syndrome associated with
macroglossia, abdominal wall defects, ear anomalies, and an increased risk for embryonic …

Abstract Background Beckwith-Wiedemann syndrome (BWS), a congenital overgrowth
disorder with variable expressivity and a predisposition to tumorigenesis, results from …