Nonalcoholic fatty liver disease (NAFLD) is a leading cause of liver disease in developed
countries. Its frequency is increasing in the general population mostly due to the widespread …

Objective: Atrial fibrillation is the most common arrhythmia after cardiac surgery. Amiodarone
can effectively prevent and control postoperative atrial and ventricular fibrillation. Acute …

Featuring more than 4100 references, Drug-Induced Liver Disease is an invaluable
reference for gastroenterologists, hepatologists, family physicians, internists, pathologists …

Potential hepatotoxicity related to amiodarone therapy is often a concern when deciding
whether to initiate or continue treatment with this medication. While mostly associated with …

Excipients are largely used as inert vehicles in formulation. Recent studies indicated that
some excipients could affect drug transport and disposition. But the effects of most excipients …

Polymers and surfactants are commonly used as excipients in oral formulations and are
generally considered to be inert. However, relatively few studies have assessed their …

Nonalcoholic steatosis/steatohepatitis is the most common cause for abnormal liver
chemistries. Apart from metabolic syndrome, drugs may also lead to development of …

Amiodarone is a benzofuran class III antiarrhythmic drug used to treat a wide spectrum of
ventricular tachyarrhythmias. The parenteral formulation is prepared in polysorbate 80 …

Amiodarone chlorhydrate is a diiodated benzofuran derivative used to treat cardiac rhythm
abnormalities. Hepatotoxicity is a relatively uncommon side effect of amiodarone and …

We report a case of intravenous (IV) amiodarone drug induced liver injury (DILI). The patient
received IV N-acetylcysteine (NAC) which resulted in a rapid improvement in liver enzymes …