[HTML][HTML] Role of sleep deprivation in immune-related disease risk and outcomes

S Garbarino, P Lanteri, NL Bragazzi… - Communications …, 2021 - nature.com
Modern societies are experiencing an increasing trend of reduced sleep duration, with
nocturnal sleeping time below the recommended ranges for health. Epidemiological and …

[HTML][HTML] Sleep medicine: Practice, challenges and new frontiers

L Parrino, P Halasz, A Szucs, RJ Thomas… - Frontiers in …, 2022 - frontiersin.org
Sleep medicine is an ambitious cross-disciplinary challenge, requiring the mutual
integration between complementary specialists in order to build a solid framework. Although …

Single-atom transition metals (Rh, Ir, Co) doped silicon carbide nanotubes (SiCNT) as nonenzymatic nitrotyrosine (NTS) sensor: Insight from theoretical calculations

GA Okon, FO Ogungbemiro, H Louis, I Benjamin… - Computational and …, 2023 - Elsevier
Abstract Transition metals Namely Rhodium (Rh), Iridium (Ir), and Cobalt (Co) doped silicon
carbide nanotube (SiCNT) surfaces were theoretically investigated using first-principles …

Interleukin‐1α and tumor necrosis factor α as an inducer for reactive‐oxygen‐species‐mediated NOD‐like receptor protein 1/NOD‐like receptor protein 3 …

Z Aghelan, S Karima, H Khazaie… - European journal of …, 2022 - Wiley Online Library
Background and purpose There is some evidence that cytokines may play an important role
in sleep deprivation; however, the underlying mechanisms are still unknown. So, the present …

[HTML][HTML] Melatonin as a Harmonizing Factor of Circadian Rhythms, Neuronal Cell Cycle and Neurogenesis: Additional Arguments for Its Therapeutic Use in …

M Shukla, B Vincent - Current Neuropharmacology, 2023 - ncbi.nlm.nih.gov
The synthesis and release of melatonin in the brain harmonize various physiological
functions. The apparent decline in melatonin levels with advanced aging is an aperture to …

[HTML][HTML] The Polygenic Risk Score Knowledge Base offers a centralized online repository for calculating and contextualizing polygenic risk scores

ML Page, EL Vance, ME Cloward, E Ringger… - Communications …, 2022 - nature.com
The process of identifying suitable genome-wide association (GWA) studies and formatting
the data to calculate multiple polygenic risk scores on a single genome can be laborious …

Risk of neurodegenerative diseases in patients with sleep disorders: a nationwide population-based case-control study

W Lin, YK Lin, FC Yang, CH Chung, JM Hu, CH Tsao… - Sleep Medicine, 2023 - Elsevier
Objective Our study aimed to explore the associative relationship between
neurodegenerative diseases and sleep disorders. Patients This 15-year retrospective …

[HTML][HTML] Circadian control of heparan sulfate levels times phagocytosis of amyloid beta aggregates

GT Clark, Y Yu, CA Urban, G Fu, C Wang, F Zhang… - PLoS …, 2022 - journals.plos.org
Alzheimer's Disease (AD) is a neuroinflammatory disease characterized partly by the
inability to clear, and subsequent build-up, of amyloid-beta (Aβ). AD has a bi-directional …

Network meta-analysis comparing the effectiveness of a prescription digital therapeutic for chronic insomnia to medications and face-to-face cognitive behavioral …

F Forma, R Pratiwadi, F El-Moustaid… - Current Medical …, 2022 - Taylor & Francis
Objective The purpose of this study was to compare the effectiveness of the only Food and
Drug Administration-authorized prescription digital therapeutic (PDT) Somryst versus face-to …

[HTML][HTML] Sleep deprivation: A risk factor for the pathogenesis and progression of Alzheimer's disease

Z Han, X Yang, S Huang - Heliyon, 2024 - cell.com
Sleep deprivation refers to an intentional or unintentional reduction in sleep time, resulting in
insufficient sleep. It is often caused by sleep disorders, work demands (eg, night shifts), and …