Anxiety and depression: what do we know of neuropeptides?
I Kupcova, L Danisovic, I Grgac, S Harsanyi - Behavioral Sciences, 2022 - mdpi.com
In modern society, there has been a rising trend of depression and anxiety. This trend
heavily impacts the population's mental health and thus contributes significantly to morbidity …
heavily impacts the population's mental health and thus contributes significantly to morbidity …
[HTML][HTML] Involvement of the opioid peptide family in cancer progression
ML Sánchez, FD Rodríguez, R Coveñas - Biomedicines, 2023 - mdpi.com
Peptides mediate cancer progression favoring the mitogenesis, migration, and invasion of
tumor cells, promoting metastasis and anti-apoptotic mechanisms, and facilitating …
tumor cells, promoting metastasis and anti-apoptotic mechanisms, and facilitating …
Targeting Nociceptin/Orphanin FQ receptor to rescue cognitive symptoms in a mouse neuroendocrine model of chronic stress
F D'Oliveira da Silva, C Robert, E Lardant… - Molecular …, 2024 - nature.com
Chronic stress causes cognitive deficits, such as impairments in episodic-like hippocampus-
dependent memory. Stress regulates an opioid-related neuropeptide named …
dependent memory. Stress regulates an opioid-related neuropeptide named …
Recovery from traumatic brain injury is nociceptin/orphanin FQ peptide receptor genotype-, sex-, and injury severity-dependent
ON Al Yacoub, HO Awwad, KM Standifer - Journal of pharmacology and …, 2024 - ASPET
Traumatic brain injury (TBI) is a leading cause of death and disability in the United States,
and survivors often experience mental and physical health consequences that reduce …
and survivors often experience mental and physical health consequences that reduce …
Endometriosis and Opioid Receptors: Are Opioids a Possible/Promising Treatment for Endometriosis?
Q Guan, RV Velho, J Sehouli, S Mechsner - International Journal of …, 2023 - mdpi.com
Endometriosis (EM), defined as the presence of endometrial-like tissue with surrounding
smooth muscle cells outside the uterus, is a disregarded gynecological disease reported to …
smooth muscle cells outside the uterus, is a disregarded gynecological disease reported to …
The Nociceptin/Orphanin FQ peptide receptor antagonist, SB-612111, improves cerebral blood flow in a rat model of traumatic brain injury
ON Al Yacoub, S Tarantini, Y Zhang… - Frontiers in …, 2023 - frontiersin.org
Traumatic brain injury (TBI) affects more than 2.5 million people in the US each year and is
the leading cause of death and disability in children and adults ages 1 to 44. Approximately …
the leading cause of death and disability in children and adults ages 1 to 44. Approximately …
Beyond monoamines: I. Novel targets and radiotracers for Positron emission tomography imaging in psychiatric disorders
With the emergence of positron emission tomography (PET) in the late 1970s, psychiatry
had access to a tool capable of non‐invasive assessment of human brain function. Early …
had access to a tool capable of non‐invasive assessment of human brain function. Early …
Regulation of N-type calcium channels by nociceptin receptors and its possible role in neurological disorders
ES Caminski, FTT Antunes, IA Souza, E Dallegrave… - Molecular Brain, 2022 - Springer
Activation of nociceptin opioid peptide receptors (NOP, aka opioid-like receptor-1, ORL-1) by
the ligand nociceptin/orphanin FQ, leads to G protein-dependent regulation of Cav2. 2 (N …
the ligand nociceptin/orphanin FQ, leads to G protein-dependent regulation of Cav2. 2 (N …
Traumatic Brain Injury Induces Nociceptin/Orphanin FQ and Nociceptin Opioid Peptide Receptor Expression within 24 Hours
ON Al Yacoub, Y Zhang, PS Patankar… - International Journal of …, 2024 - mdpi.com
Traumatic brain injury (TBI) is a major cause of mortality and disability around the world, for
which no treatment has been found. Nociceptin/Orphanin FQ (N/OFQ) and the nociceptin …
which no treatment has been found. Nociceptin/Orphanin FQ (N/OFQ) and the nociceptin …
The N/Ofq-Nop receptor system: a potential therapeutic target for traumatic brain injury
ON Al Yacoub - 2023 - search.proquest.com
Traumatic brain injury (TBI) is a major cause of mortality and disability around the world. To
date, no pharmacological agent has received FDA approval to treat or improve recovery of …
date, no pharmacological agent has received FDA approval to treat or improve recovery of …