Adenocarcinoma spectrum lesions of the lung: Detection, pathology and treatment strategies
L Succony, DM Rassl, AP Barker, FM McCaughan… - Cancer treatment …, 2021 - Elsevier
Adenocarcinoma has become the most prevalent lung cancer sub-type and its frequency is
increasing. The earliest stages in the development of lung adenocarcinomas are visible …
increasing. The earliest stages in the development of lung adenocarcinomas are visible …
Heterogeneity in lung cancer
VML de Sousa, L Carvalho - Pathobiology, 2018 - karger.com
Lung cancer diagnosis is a challenge since it is also one of the most frequently diagnosed
cancers. Diagnostic challenges are deeply related to the development of personalized …
cancers. Diagnostic challenges are deeply related to the development of personalized …
EGFR mutations and lung cancer
G da Cunha Santos, FA Shepherd… - Annual Review of …, 2011 - annualreviews.org
Epidermal growth factor receptor (EGFR) is a transmembrane protein with cytoplasmic
kinase activity that transduces important growth factor signaling from the extracellular milieu …
kinase activity that transduces important growth factor signaling from the extracellular milieu …
Large-scale determination of absolute phosphorylation stoichiometries in human cells by motif-targeting quantitative proteomics
Our ability to model the dynamics of signal transduction networks will depend on accurate
methods to quantify levels of protein phosphorylation on a global scale. Here we describe a …
methods to quantify levels of protein phosphorylation on a global scale. Here we describe a …
Diagnosis of lung adenocarcinoma in resected specimens: implications of the 2011 International Association for the Study of Lung Cancer/American Thoracic Society …
WD Travis, E Brambilla, M Noguchi… - … of Pathology and …, 2013 - meridian.allenpress.com
A new lung adenocarcinoma classification has been published by the International
Association for the Study of Lung Cancer, the American Thoracic Society, and the European …
Association for the Study of Lung Cancer, the American Thoracic Society, and the European …
The challenge of NSCLC diagnosis and predictive analysis on small samples. Practical approach of a working group
E Thunnissen, KM Kerr, FJF Herth, S Lantuejoul… - Lung cancer, 2012 - Elsevier
Until recently, the division of pulmonary carcinomas into small cell lung cancer (SCLC) and
non-small cell lung cancer (NSCLC) was adequate for therapy selection. Due to the …
non-small cell lung cancer (NSCLC) was adequate for therapy selection. Due to the …
Heterogeneous Distribution of EGFR Mutations Is Extremely Rare in Lung Adenocarcinoma
Purpose Some studies have shown that epidermal growth factor receptor (EGFR) mutations
can be heterogeneously distributed in individual tumors. In this study, we re-evaluated the …
can be heterogeneously distributed in individual tumors. In this study, we re-evaluated the …
Prognostic and predictive implications of HER2/ERBB2/neu gene mutations in lung cancers
K Tomizawa, K Suda, R Onozato, T Kosaka, H Endoh… - Lung cancer, 2011 - Elsevier
BACKGROUND: Activating mutation in the kinase domain of the human EGF receptor 2
(HER2) gene (also known as ERBB2 or neu) is reported to be present in a small fraction of …
(HER2) gene (also known as ERBB2 or neu) is reported to be present in a small fraction of …
[HTML][HTML] High incidence of EGFR mutations in Korean men smokers with no intratumoral heterogeneity of lung adenocarcinomas: correlation with histologic subtypes …
PL Sun, H Seol, HJ Lee, SB Yoo, H Kim, X Xu… - Journal of Thoracic …, 2012 - Elsevier
Introduction: Epidermal growth factor receptor (EGFR) mutation has been known to be
associated with adenocarcinoma with bronchioloalveolar carcinoma (BAC; lepidic) feature …
associated with adenocarcinoma with bronchioloalveolar carcinoma (BAC; lepidic) feature …
[HTML][HTML] ΔNp63 (p40) and thyroid transcription factor-1 immunoreactivity on small biopsies or cellblocks for typing non-small cell lung cancer: a novel two-hit, sparing …
Introduction: Diagnosing non-small cell lung cancer on biopsy/cellblock samples by
morphology may be demanding. As sparing material for molecular testing is mandatory, a …
morphology may be demanding. As sparing material for molecular testing is mandatory, a …