The GATA family of transcription factors consists of six proteins (GATA1-6) which are
involved in a variety of physiological and pathological processes. GATA1/2/3 are required …

The human β‐globin gene locus is the subject of intense study, and over the past two
decades a wealth of information has accumulated on how tissue‐specific and stage‐specific …

Metastasis of epithelial tumor cells can be associated with the acquisition of fibroblastoid
features and the ability to invade stroma and blood vessels. Using matched in vivo and in …

Members of the GATA family of transcription factors, which are related by a high degree of
amino acid sequence identity within their zinc finger DNA-binding domains, each show …

Malignant transformation usually inhibits terminal cell differentiation but the precise
mechanisms involved are not understood. PU. 1 is a hematopoietic-specific Ets family …

The transcription factor GATA-1 is expressed in early hematopoietic progenitors and
specifically down-regulated in myelomonocytic cells during lineage determination. Our …

As the major proteins of adult keratinocytes, keratins provide biochemical markers for
exploring mouse epidermal embryogenesis. Here, we used a modified method of whole …

Gene inactivation studies have shown that members of the GATA family of transcription
factors are critical for endoderm differentiation in mice, flies and worms, yet how these …

We describe experiments which show that: 1) two previously identified members of the
GATA family of transcription factors (both of which were originally called GATA-4) …

Mouse embryos deficient in Gata3 die by 11 days post coitum (dpc) from pathology of
undetermined origin 1. We recently showed that Gata3-directed lacZ expression of a 625-kb …