Menthol targeting AMPK alleviates the inflammatory response of bovine mammary epithelial cells and restores the synthesis of milk fat and milk protein

S Liu, W Guo, Y Jia, B Ye, S Liu, S Fu, J Liu… - Frontiers in …, 2021 - frontiersin.org
Mastitis is one of the most serious diseases that causes losses in the dairy industry,
seriously impairing milk production and milk quality, and even affecting human health …

Differential expression profiles of lncRNA following LPS-induced inflammation in bovine mammary epithelial cells

JP Wang, QC Hu, J Yang, ZM Luoreng… - Frontiers in Veterinary …, 2021 - frontiersin.org
Bovine mastitis is an inflammatory response of mammary glands caused by pathogenic
microorganisms such as Escherichia coli (E. coli). As a key virulence factor of E. coli …

Niacin/β-hydroxybutyrate regulates milk fat and milk protein synthesis via the GPR109A/G i/mTORC1 pathway

J Chen, T Lin, S Zhang, X Yue, XH Liu, C Wu… - Food & Function, 2023 - pubs.rsc.org
As a crucial receptor of BHBA and niacin, GPR109A is largely expressed in the mammary
gland. However, the role of GPR109A in milk synthesis and its underlying mechanism is still …

[HTML][HTML] ETEC regulates GPR109A expression in intestinal epithelial cells mediated by inflammatory factors secreted by macrophages

B Yuan, M Liu, S Luo, Q Qu, M Zhu, Z Wang… - Research in Veterinary …, 2023 - Elsevier
Gut microbes control host immunity and homeostasis, and their abnormal changes are
associated with the occurrence and development of diseases. GPR109A is an essential …

Hydroxycarboxylic acid receptor 2 (HCA2) agonists induce NET formation and MMP-9 release from bovine polymorphonuclear leukocytes

MD Carretta, P Creutzburg, K Borquez… - Developmental & …, 2023 - Elsevier
Periparturient cows are commonly fed diets supplemented with Niacin (nicotinic acid, NA)
because of its anti-lipolytic properties. NA confers its anti-lipolytic effects by activating the …

[HTML][HTML] Wogonin attenuates inflammation and oxidative stress in lipopolysaccharide-induced mastitis by inhibiting Akt/NF-κB pathway and activating the Nrf2/HO-1 …

X He, J Wang, L Sun, W Ma, M Li, S Yu, Q Zhou… - Cell Stress and …, 2023 - Elsevier
Mastitis is a disease involved in inflammation of breast which affects human and animals.
Wogonin is one bioactive compound from many Chinese herbal medicines, which have …

[HTML][HTML] The preventive effects of Lactobacillus casei 03 on Escherichia coli-induced mastitis in vitro and in vivo

K Li, M Yang, M Tian, L Jia… - Journal of …, 2024 - journal-inflammation.biomedcentral …
Lactobacillus casei possesses many kinds of bioactivities, such as anti-inflammation and
anti-oxidant, and has been applied to treating multiple inflammatory diseases. However, its …

Protective Effects of Niacin on Rumen Epithelial Cell Barrier Integrity in Heat-Stressed Beef Cattle

B Zou, F Long, F Xue, C Chen, X Zhang, M Qu, L Xu - Animals, 2024 - mdpi.com
Simple Summary Heat stress can easily cause a series of physiological hazards in beef
cattle, affecting the rumen barrier function and, ultimately, beef cattle performance. As a B …

Niacin inhibits the synthesis of milk fat in BMECs through the GPR109A-mediated downstream signalling pathway

J Wang, Y Cao, S Fu, W Li, Y Ge, J Cheng, J Liu - Life Sciences, 2020 - Elsevier
Aims Previous studies have shown the effect of niacin on dairy cow production, but no study
on the role of niacin in milk fat synthesis has been performed. Therefore, the purpose of this …

烟酸对脂肪代谢的影响及其作用机制.

龙凡, 瞿明仁, 邹必成, 陈传斌, 许兰娇 - Feed Research, 2022 - search.ebscohost.com
烟酸(NA) 是动物必需维生素之一, 在动物三大营养物质代谢中起着至关重要的作用,
作为烟酰胺腺嘌呤二核苷酸(NAD) 和烟酰胺腺嘌呤二核苷酸磷酸(NADP) 的前体 …