Amyotrophic lateral sclerosis is a degenerative disease affecting the motor neurons. In spite
of our growing insights into its biology, it remains a lethal condition. The identification of the …

Aggregation of misfolded protein and resultant intracellular inclusion body formation are
common hallmarks of mutant superoxide dismutase (mSOD1)-linked familial amyotrophic …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the
progressive and fatal loss of motor neurons. In ALS, there is a significant cell proliferation in …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease which currently
lacks effective treatments. Mutations in the RNA-binding protein FUS are a common cause of …

Amyotrophic lateral sclerosis (ALS) is a multifactorial and progressive neurodegenerative
disease of unknown etiology. Due to ALS's unpredictable onset and progression rate, the …

Mutations in fused in sarcoma (FUS) lead to amyotrophic lateral sclerosis (ALS) with varying
ages of onset, progression and severity. This suggests that unknown genetic factors …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that affects mainly
motor neurons (MNs). NSC-34 MN-like cells carrying the G93A mutation in human …

Amyotrophic lateral sclerosis (ALS) is a chronic neurodegenerative disease characterized
by progressive degeneration of the motor neurons in the cortex, brainstem, and spinal cord …

Motor neuron diseases (MNDs) are a group of neurological disorders that selectively affect
motor neurons. There are currently no cures or efficacious treatments for these diseases. In …

MicroRNAs (miRNAs) have rapidly emerged as biologically important mediators of
posttranscriptional and epigenetic regulation in both plants and animals. miRNAs function …