Genomic technologies have led to tremendous gains in understanding how pathogens
function, evolve and interact. Pathogen diversity is now measurable at high precision and …

Achieving a malaria-free world presents exciting scientific challenges as well as
overwhelming health, equity, and economic benefits. WHO and countries are setting …

Antibiotic-resistant bacterial infections are a major concern to public health. Phage therapy
has been proposed as a promising alternative to antibiotics, but an increasing number of …

To date, six clinical trials have explored the efficacy of pre-exposure prophylaxis (PrEP)
against HIV infection using oral tenofovir and/or emtricitabine/tenofovir [1–6]. Efficacy ranged …

Methods: A stochastic computer simulation model of HIV infection and the effect of ART was
used to estimate life expectancy and determine the distribution of potential lifetime outcomes …

Sexually transmitted co-infections increase HIV infectiousness through local inflammatory
processes. The prevalence of STI among people living with HIV/AIDS has implications for …

Background Antiretroviral drugs reduce viral replication and can reduce mother‐to‐child
transmission of HIV either by lowering plasma viral load in pregnant women or through post …

Despite antiretroviral therapy (ART), people living with human immunodeficiency virus
(HIV)(PLWH) continue to experience chronic inflammation and immune dysfunction, which …

Introduction: Successful population-level antiretroviral therapy (ART) adherence will be
necessary to realize both the clinical and prevention benefits of antiretroviral scale-up and …

Plaque‐induced periodontal diseases occur in response to the accumulation of dental
plaque. Disease manifestation and progression is determined by the nature of the immune …