Design principles of microneedles for drug delivery and sampling applications
Microneedles technology is a powerful platform to achieve efficient transdermal delivery of
bioactive molecules for local or systemic therapies attributing to their minimally invasive …
bioactive molecules for local or systemic therapies attributing to their minimally invasive …
Trial watch: chemotherapy-induced immunogenic cell death in oncology
Immunogenic cell death (ICD) refers to an immunologically distinct process of regulated cell
death that activates, rather than suppresses, innate and adaptive immune responses. Such …
death that activates, rather than suppresses, innate and adaptive immune responses. Such …
Synergistic reinforcing of immunogenic cell death and transforming tumor‐associated macrophages via a multifunctional cascade bioreactor for optimizing cancer …
C Huang, B Lin, C Chen, H Wang, X Lin… - Advanced …, 2022 - Wiley Online Library
Immunogenic cell death (ICD) has aroused widespread attention because it can reconstruct
a tumor microenvironment and activate antitumor immunity. This study proposes a two‐way …
a tumor microenvironment and activate antitumor immunity. This study proposes a two‐way …
Microneedle patch integrated with porous silicon confined dual nanozymes for synergistic and hyperthermia‐enhanced nanocatalytic ferroptosis treatment of …
J Zhao, W Duan, X Liu, F Xi, J Wu - Advanced Functional …, 2023 - Wiley Online Library
Superficial melanoma is the deadliest form of skin cancer without desirable clinically
therapeutic options. Nanozymes, artificial nanomaterials with physicochemical performance …
therapeutic options. Nanozymes, artificial nanomaterials with physicochemical performance …
Marine‐Derived Hydrogels for Biomedical Applications
X Lin, J Wang, X Wu, Y Luo, Y Wang… - Advanced Functional …, 2023 - Wiley Online Library
Marine organisms provide novel and broad sources for the preparations and applications of
biomaterials. Since the urgent requirement of bio‐hydrogels to mimic tissue extracellular …
biomaterials. Since the urgent requirement of bio‐hydrogels to mimic tissue extracellular …
Research progress of microneedles in the treatment of melanoma
X Li, Z Zhao, M Zhang, G Ling, P Zhang - Journal of controlled release, 2022 - Elsevier
Melanoma is an aggressive malignancy deriving from melanocytes, which is characterized
by high tendency of metastases and mortality rate. Current therapies for melanoma, like …
by high tendency of metastases and mortality rate. Current therapies for melanoma, like …
Highly sensitive and reliable internal-standard surface-enhanced Raman scattering microneedles for determination of bacterial metabolites as infection biomarkers in …
R Mei, Y Wang, S Shi, X Zhao, Z Zhang… - Analytical …, 2022 - ACS Publications
Microneedles (MNs) are currently one of the most promising tools for skin interstitial fluid
(ISF)-based biosensing, while it is still a challenge to expand the detectable biomarkers in …
(ISF)-based biosensing, while it is still a challenge to expand the detectable biomarkers in …
[HTML][HTML] Polysaccharide-based transdermal drug delivery
J Li, H Xiang, Q Zhang, X Miao - Pharmaceuticals, 2022 - mdpi.com
Materials derived from natural plants and animals have great potential for transdermal drug
delivery. Polysaccharides are widely derived from marine, herbal, and microbial sources …
delivery. Polysaccharides are widely derived from marine, herbal, and microbial sources …
Steerable microneedles enabling deep delivery of photosensitizers and CRISPR/Cas9 systems for effective combination cancer therapy
T Wang, G Chen, S Zhang, D Li, G Wei, X Zhao… - Nano Letters, 2023 - ACS Publications
Although gene therapy has shown prospects in treating triple-negative breast cancer, it is
insufficient to treat such a malignant tumor. Herein, nanoparticles (NPs)-embedded …
insufficient to treat such a malignant tumor. Herein, nanoparticles (NPs)-embedded …
Photothermal and acid-responsive Fucoidan-CuS bubble pump microneedles for combined CDT/PTT/CT treatment of melanoma
J Tao, B Wang, Y Dong, XY Chen, S Li… - … Applied Materials & …, 2023 - ACS Publications
Transdermal cancer therapy faces great challenges in clinical practice due to the low drug
transdermal efficiency and the unsatisfactory effect of monotherapy. Herein, we develop a …
transdermal efficiency and the unsatisfactory effect of monotherapy. Herein, we develop a …