Ovarian cancer is the fifth leading cause of cancer death among women and the most lethal
gynecologic malignancy. One of the leading causes of death in high-grade serous ovarian …

Ovarian cancer remains a challenging disease with limited treatment options and poor
prognosis. The tumor microenvironment (TME) plays a crucial role in tumor growth …

Tumor angiogenesis is an essential process for growth and metastasis of cancer cells as it
supplies tumors with oxygen and nutrients. During tumor angiogenesis, many pro …

Failure in ovarian cancer therapy, following cytoreduction and chemotherapy, is related to
the presence of cancer stem cells-a small subpopulation of cells resistant to chemotherapy …

Ovarian Cancer (OC) is the most common gynaecological malignancy and the eighth most
diagnosed cancer in females worldwide. Presently, it ranks as the fifth leading cause of …

Angiogenesis is a hallmark of ovarian cancer (OC); the ingrowth of blood vessels promotes
rapid cell growth and the associated metastasis. Melatonin is a well-characterized …

Pazopanib is a relatively new compound to be introduced into the chemotherapy field. It is
thought to have decent anti-angiogenic properties, which gives an additional hope for the …

Ovarian cancer (OC) remains the most fatal disease of gynecologic malignant tumors.
Angiogenesis refers to the development of new vessels from pre-existing ones, which is …

In the present study, we constructed the recombinant plasmid IL10-PEGFP-C1 and
successfully transfected into human mesenchymal stem cells. After culturing for 72 h, the …

Objectives: Angiogenesis targeting is an attractive approach for cancer treatment. Delta-like
ligand 4 (DLL4) plays a pivotal role in neovascular development and its inhibitors have …