Quercetin, a naturally non-toxic flavonoid within the safe dose range with antioxidant, anti-
apoptotic and anti-inflammatory properties, plays an important role in the treatment of aging …

Aging entails the inevitable loss of the structural and functional integrity of cells and tissues
during the lifetime. It is a highly hormone-dependent process; although, the exact …

Astrocytes contribute to brain inflammation in neurological disorders but the molecular
mechanisms controlling astrocyte reactivity and their relationship to neuroinflammatory …

With the development of social economics and the increase of working pressure, more and
more women are suffering from long-term serious stress and showing symptoms of …

Sirt1, a member of the sirtuins family, is a nicotinamide adenosine dinucleotide (NAD+)-
dependent deacetylase. It can be involved in the regulation of several processes including …

Depression is a neurological disorder that profoundly affects human physical and mental
health, resulting in various changes in the central nervous system. Despite several …

Intracerebroventricular infusion of resolvin E1 (RvE1), a bioactive metabolite derived from
eicosapentaenoic acid, exerts antidepressant-like effects in a mouse model of …

Background Inflammation is present in neurological and peripheral disorders. Thus,
targeting inflammation has emerged as a viable option for treating these disorders. Previous …

Inflammatory responses by macrophages have been pivotal in the pathogenesis of various
diseases. We previously demonstrated the anti-inflammatory effects of ginsenoside …

A significant decrease in estrogen levels puts menopausal women at high risk for major
depression, which remains difficult to cure despite its relatively clear etiology. With the …