Design of a zero-order sustained release PLGA microspheres for palonosetron hydrochloride with high encapsulation efficiency

Z Yang, L Liu, L Su, X Wu, Y Wang, L Liu… - International journal of …, 2020 - Elsevier
Efficient encapsulation of hydrophilic drugs was substantially challenging when using
emulsion solvent evaporation approach. The aim of present study was to design …

[HTML][HTML] Comparative study between fosaprepitant and palonosetron in the prophylaxis of postoperative nausea and vomiting in women undergoing laparoscopic …

ELC Braga, N Verçosa, IL Cavalcanti - Frontiers in Pharmacology, 2022 - frontiersin.org
Objective: To test the hypothesis that the single use of fosaprepitant is not inferior to the use
of palonosetron as antiemetic prophylaxis in the first 48 h after surgery in women …

[PDF][PDF] Study of the Mechanism of Antiemetic Effect of Lavandula angustifolia Mill. Essential Oil Based on Ca2+/CaMKII/ERK1/2 Pathway

J Li, X Wang, S Xun, Q Guo, Y Wang, Y Jia… - Drug Design …, 2022 - Taylor & Francis
Purpose To investigate the effective components and possible mechanism of action of
Lavandula angustifolia Mill. essential oil (LEO) in preventing vomiting through the olfactory …

[HTML][HTML] Risk factors associated with chemotherapy-induced nausea in the week before the next cycle and impact of nausea on quality of life outcomes

KP Singh, KM Kober, AA Dhruva, E Flowers… - Journal of Pain and …, 2018 - Elsevier
Context Despite current advances in antiemetic treatments, between 19% and 58% of
oncology patients experience chemotherapy-induced nausea (CIN). Objectives Aims of this …

Ten-year trends in antiemetic prescribing in patients receiving highly emetogenic chemotherapy

CC O'Sullivan, HK Van Houten… - Journal of the National …, 2018 - jnccn.org
Purpose: Prevention of chemotherapy-induced nausea and vomiting is essential to preserve
quality of life in patients with cancer receiving highly emetogenic chemotherapy (HEC) …

Use of palonosetron and ondansetron in the prophylaxis of postoperative nausea and vomiting in women 60 years of age or older undergoing laparoscopic …

ELC Braga, NV Figueiredo, L Barrucand… - European Journal of …, 2019 - journals.lww.com
Palonosetron is a second-generation 5-HT3 antagonist initially used in the prevention of
nausea and vomiting associated with chemotherapy. 1 It differs from the other serotonergic …

Toxicidades Gastrointestinais em Mulheres durante Tratamento Quimioterápico do Câncer de Mama

SY Kameo, BF Amorim, R Barbosa-Lima… - Revista Brasileira de …, 2021 - rbc.inca.gov.br
Introdução: Os agentes quimioterápicos para o tratamento do câncer de mama
frequentemente provocam toxicidades sistêmicas nas pacientes, incluindo alterações …

The clinical problem of chemotherapy-induced nausea and vomiting

B Rapoport - Oncology, 2016 - go.gale.com
Over the past 2 decades, substantial advances have been made in the management of
chemotherapy-induced nausea and vomiting (CINV). This is primarily because of a deeper …

Estudo comparativo entre fosaprepitanto e palonosetrona na profilaxia de náuseas e vômitos pós-operatórios em mulheres submetidas a colecistectomias …

ELC Braga - 2023 - app.uff.br
CONTEXTO: Apesar da investigação contínua e do desenvolvimento de novos fármacos e
técnicas, as náuseas e vômitos no pós-operatório (NVPO) são frequentes, geram …

[PDF][PDF] Aspects of interest related to antiemesis in haematological patients

MPF Gonzalez, AMG Marquez, MP Sanchez - Hematol Transfus Int …, 2019 - academia.edu
Few side effects of cancer treatment are more fearsome for patients than nausea and
vomiting. Although both can result from surgery or radiation therapy, chemotherapy-induced …