Epidemiology of heart failure with preserved ejection fraction

SM Dunlay, VL Roger, MM Redfield - Nature Reviews Cardiology, 2017 - nature.com
Heart failure (HF) with preserved ejection fraction (HFpEF) is a clinical syndrome associated
with poor quality of life, substantial health-care resource utilization, and premature mortality …

[HTML][HTML] Understanding the epidemiology of heart failure to improve management practices: an Asia-Pacific perspective

J Rajadurai, HF Tse, CH Wang, NI Yang, J Zhou… - Journal of cardiac …, 2017 - Elsevier
Heart failure (HF) is a major global healthcare problem with an estimated prevalence of
approximately 26 million. In Asia-Pacific regions, HF is associated with a significant …

Mortality associated with heart failure with preserved vs. reduced ejection fraction in a prospective international multi-ethnic cohort study

CSP Lam, GD Gamble, LH Ling, D Sim… - European heart …, 2018 - academic.oup.com
Aims Whether prevalence and mortality of patients with heart failure with preserved or mid-
range (40–49%) ejection fraction (HFpEF and HFmREF) are similar to those of heart failure …

Right ventricular dysfunction in left‐sided heart failure with preserved versus reduced ejection fraction

L Bosch, CSP Lam, L Gong, SP Chan… - European journal of …, 2017 - Wiley Online Library
Background Right ventricular (RV) dysfunction is recognized as a major prognostic factor in
left‐sided heart failure (HF). However, the relative contribution of RV dysfunction in HF with …

Growth differentiation factor 15 in heart failure with preserved vs. reduced ejection fraction

MMY Chan, R Santhanakrishnan… - European journal of …, 2016 - Wiley Online Library
Aim Growth differentiation factor 15 (GDF15) is a cytokine highly expressed in states of
inflammatory stress. We aimed to study the clinical correlates and prognostic significance of …

Circulating microRNAs in heart failure with reduced and preserved left ventricular ejection fraction

LL Wong, A Armugam, S Sepramaniam… - European journal of …, 2015 - Wiley Online Library
Aim The potential diagnostic utility of circulating microRNAs in heart failure (HF) or in
distinguishing HF with reduced vs. preserved left ventricular ejection fraction (HFREF and …

Association of diabetes mellitus on cardiac remodeling, quality of life, and clinical outcomes in heart failure with reduced and preserved ejection fraction

J Yap, WT Tay, THK Teng, I Anand… - Journal of the …, 2019 - Am Heart Assoc
Background Diabetes mellitus frequently coexists with heart failure (HF), but few studies
have compared the associations between diabetes mellitus and cardiac remodeling, quality …

The effectiveness of a nurse-led home-based heart failure self-management programme (the HOM-HEMP) for patients with chronic heart failure: a three-arm stratified …

Y Jiang, KWL Koh, HJ Ramachandran… - International Journal of …, 2021 - Elsevier
Background Although important, heart failure self-care remains a challenge for many
patients. This study aimed to evaluate the effect of a nurse-led, home-based self …

Iron deficiency in a multi‐ethnic Asian population with and without heart failure: prevalence, clinical correlates, functional significance and prognosis

TJ Yeo, PSD Yeo, R Ching‐Chiew Wong… - European journal of …, 2014 - Wiley Online Library
Aims Current heart failure (HF) guidelines highlight the importance of iron deficiency (ID) in
HF. Whether HF itself or age‐related comorbidities contribute to ID is uncertain, and …

Myeloperoxidase inhibition reverses biomarker profiles associated with clinical outcomes in HFpEF

E Michaëlsson, LH Lund, C Hage, SJ Shah, AA Voors… - Heart Failure, 2023 - jacc.org
Background Systemic microvascular dysfunction and inflammation are postulated to play a
pathophysiologic role in heart failure with preserved ejection fraction (HFpEF). Objectives …