Primary ciliary dyskinesia (PCD) is a rare genetic disorder characterized by impaired motile
cilia function, particularly in the upper and lower airways. To date, more than 50 causative …

Nontuberculous mycobacteria (NTM) are environmental and ubiquitous, but only a few
species are associated with disease, often presented as nodular/bronchiectatic or cavitary …

Motile cilia have essential cellular functions in development, reproduction, and homeostasis.
Genetic causes for motile ciliopathies have been identified, but the consequences on …

A core pathophysiologic feature underlying many respiratory diseases is multiciliated cell
dysfunction, leading to inadequate mucociliary clearance. Due to the prevalence and highly …

Motile cilia assembly utilizes over 800 structural and cytoplasmic proteins. Variants in
approximately 58 genes cause primary ciliary dyskinesia (PCD) in humans, including the …

Motile cilia are complex organelles comprised of> 800 structural proteins. Variants in 58 of
these genes cause primary ciliary dyskinesia (PCD) in humans. We used a second-site non …