Pan-genome is defined as the set of orthologous and unique genes of a specific group of
organisms. The pan-genome is composed by the core genome, accessory genome, and …

Abstract Background The 16S rRNA gene is used extensively in bacterial phylogenetics, in
species delineation, and now widely in microbiome studies. However, the gene suffers from …

The Mitis group of streptococci includes an important human pathogen, Streptococcus
pneumoniae (pneumococcus) and about 20 other related species with much lower …

Bacterial genomes can contain traces of a complex evolutionary history, including extensive
homologous recombination, gene loss, gene duplications, and horizontal gene transfer. To …

Streptococcus dentisani 7746, isolated from dental plaque of caries-free individuals, has
been shown to have several beneficial effects in vitro which could contribute to promote oral …

Complex polymicrobial biofilm communities are abundant in nature particularly in the human
oral cavity where their composition and fitness can affect health. While the study of these …

A detailed understanding of where bacteria localize is necessary to advance microbial
ecology and microbiome‐based therapeutics. The site‐specialist hypothesis predicts that …

Rationale The most common antibiotic used to treat people with cystic fibrosis (PWCF) is
inhaled tobramycin, administered as maintenance therapy for chronic Pseudomonas …

Industrialization—including urbanization, participation in the global food chain and
consumption of heavily processed foods—is thought to drive substantial shifts in the human …

Research into the lower urinary tract (LUT) microbiota has primarily focused on its
relationship to LUT symptoms (LUTS), taking snapshots of these communities in individuals …